Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2023 Nov 13:17:3419-3427.
doi: 10.2147/OPTH.S433530. eCollection 2023.

Early Clinical Experience with a New Hydrophobic Acrylic Single-Piece Monofocal Intraocular Lens

Steven C Schallhorn  1   2   3 , David Teenan  2 , Jan A Venter  2 , Julie M Schallhorn  1   4 , Stephen J Hannan  2
Affiliations

Early Clinical Experience with a New Hydrophobic Acrylic Single-Piece Monofocal Intraocular Lens

Steven C Schallhorn et al. Clin Ophthalmol. .

Abstract

Purpose: To evaluate early clinical outcomes and adverse events (AEs) in cataract patients following implantation of a monofocal hydrophobic acrylic IOL with a new optimized non-constant aberration-correcting design (CT LUCIA 621P).

Methods: This retrospective study included patients with visually significant cataracts who underwent implantation of the CT LUCIA 621P IOL. Refraction, corrected (CDVA) and uncorrected (UDVA) visual acuity of the last available visit were used in the analysis. Intraoperative and postoperative AEs of the cohort were reviewed.

Results: A total of 191 eyes of 133 patients with the mean age of 70.2±11.2 years were included in this study. The mean follow-up time of the last available visit was 1.7±1.3 months. The mean postoperative monocular UDVA was 0.09±0.16 logMAR (≈20/25), and 74.9% (143/191) eyes achieved ≥20/25 UDVA. The percentage of eyes with manifest spherical equivalent (MSE) within ±0.50D and ±1.00D of emmetropia was 84.8% (162/191) and 98.4% (188/191), respectively. Linear regression of attempted vs achieved MSE showed a tight relationship, with the coefficient of determination close to 1 (R2=0.99), indicating a very predictable refractive correction. The reported AEs were those typically expected after cataract surgery. There were no AEs related to intraoperative manipulation with the IOL/injector or to postoperative stability of the IOL in the capsular bag. No eye lost ≥2 lines of CDVA.

Conclusion: The implantation of CT LUCIA 621P resulted in good refractive predictability and visual outcomes. No IOL-related adverse events were reported.

Keywords: cataract surgery; monofocal IOL; non-constant aberration-correcting optic design.

PubMed Disclaimer

Conflict of interest statement

Steven Schallhorn is a chief medical officer for Carl Zeiss Meditec and a chairman of medical advisory board for Optical Express. Stephen Hannan, Jan Venter, and David Teenan are employees of Optical Express. Julie Schallhorn received personal fees from Carl Zeiss Meditec, Allergan, Long Bridge, and Forsight V6 and has a financial interest in Journey 1, Neurotrigger, and Novus Vision. The authors report no other conflicts of interest in this work.

Figures

Figure 1
Figure 1
CT LUCIA 621P IOL.
Figure 2
Figure 2
BLUESERTTM injector.
Figure 3
Figure 3
Cumulative postoperative uncorrected distance visual acuity (UDVA) vs cumulative postoperative corrected distance visual acuity (CDVA).
Figure 4
Figure 4
Scattergram of attempted vs achieved manifest spherical equivalent (D – diopter).
Figure 5
Figure 5
Distribution of postoperative manifest spherical equivalent (MSE – manifest spherical equivalent, D – diopter).
See this image and copyright information in PMC

References

    1. Taketani F, Yukawa E, Yoshii T, Sugie Y, Hara Y. Influence of intraocular lens optical design on high-order aberrations. J Cataract Refract Surg. 2005;31(5):969–972. doi:10.1016/j.jcrs.2004.10.064 - DOI - PubMed
    1. Schuster AK, Tesarz J, Vossmerbaeumer U. Ocular wavefront analysis of aspheric compared with spherical monofocal intraocular lenses in cataract surgery: systematic review with metaanalysis. J Cataract Refract Surg. 2015;41(5):1088–1097. doi:10.1016/j.jcrs.2015.04.005 - DOI - PubMed
    1. Lawu T, Mukai K, Matsushima H, Senoo T. Effects of decentration and tilt on the optical performance of 6 aspheric intraocular lens designs in a model eye. J Cataract Refract Surg. 2019;45(5):662–668. doi:10.1016/j.jcrs.2018.10.049 - DOI - PubMed
    1. Liu Y, Zhao J, Hu Y, Li B, Wang J, Zhang J. Comparison of the visual performance after implantation of three aberration-correcting aspherical intraocular lens. Curr Eye Res. 2021;46(3):333–340. doi:10.1080/02713683.2020.1798467 - DOI - PubMed
    1. Schmid R. Early experience with the aspheric CT LUCIA 621P IOL. Host of design features add up to reliable optical performance. Ophthalmology Times. Available from: https://europe.ophthalmologytimes.com/microsites/zeiss-cataract-laser-vi.... Accessed September 21, 2023.