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Review
. 2024;27(13):1861-1876.
doi: 10.2174/0113862073265604231106112203.

Computational Approaches: A New Frontier in Cancer Research

Shubham Srivastava  1 , Pushpendra Jain  1
Affiliations
Review

Computational Approaches: A New Frontier in Cancer Research

Shubham Srivastava et al. Comb Chem High Throughput Screen. 2024.

Abstract

Cancer is a broad category of disease that can start in virtually any organ or tissue of the body when aberrant cells assault surrounding organs and proliferate uncontrollably. According to the most recent statistics, cancer will be the cause of 10 million deaths worldwide in 2020, accounting for one death out of every six worldwide. The typical approach used in anti-cancer research is highly time-consuming and expensive, and the outcomes are not particularly encouraging. Computational techniques have been employed in anti-cancer research to advance our understanding. Recent years have seen a significant and exceptional impact on anticancer research due to the rapid development of computational tools for novel drug discovery, drug design, genetic studies, genome characterization, cancer imaging and detection, radiotherapy, cancer metabolomics, and novel therapeutic approaches. In this paper, we examined the various subfields of contemporary computational techniques, including molecular docking, artificial intelligence, bioinformatics, virtual screening, and QSAR, and their applications in the study of cancer.

Keywords: Computational approach; QSAR; artificial intelligence; bioinformatics; cancer; cancer diagnosis.; machine learning; virtual screening.

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