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Editorial
. 2024 Mar;129(3):459-460.
doi: 10.1002/jso.27537. Epub 2023 Nov 30.

Is the watch-and-wait strategy suitable for every patient who has achieved a complete clinical response with neoadjuvant treatment in locally advanced rectum cancer?

Selin Akturk Esen  1 , Dogan Uncu  1
Affiliations
Editorial

Is the watch-and-wait strategy suitable for every patient who has achieved a complete clinical response with neoadjuvant treatment in locally advanced rectum cancer?

Selin Akturk Esen et al. J Surg Oncol. 2024 Mar.
No abstract available

Keywords: clinical complete response; pathological complete response; rectum cancer; watch-and-wait strategy.

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References

REFERENCES

    1. Conroy T, Bosset JF, Etienne PL, et al. Neoadjuvant chemotherapy with FOLFIRINOX and preoperative chemoradiotherapy for patients with locally advanced rectal cancer (UNICANCER-PRODIGE 23): a multicentre, randomised, open-label, phase 3 trial. Lancet Oncol. 2021;22:702-715. doi:10.1016/S1470-2045(21)00079-6
    1. You YN, Hardiman KM, Bafford A, et al. The American Society of Colon and Rectal Surgeons clinical practice guidelines for the management of rectal cancer. Dis Colon Rectum. 2020;63:1191-1222. doi:10.1097/DCR.0000000000001762
    1. Hiotis SP, Weber SM, Cohen AM, et al. Assessing the predictive value of clinical complete response to neoadjuvant therapy for rectal cancer: an analysis of 488 patients. J Am Coll Surg. 2002;194:131-135.
    1. discussion 135-136. doi:10.1016/s1072-7515(01)01159-0
    1. Smith FM, Chang KH, Sheahan K, Hyland J, O'Connell PR, Winter DC. The surgical significance of residual mucosal abnormalities in rectal cancer following neoadjuvant chemoradiotherapy. Br J Surg. 2012;99:993-1001. doi:10.1002/bjs.8700

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