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Case Reports
. 2023 Nov-Dec;14(6):100812.
doi: 10.1016/j.jaim.2023.100812. Epub 2023 Nov 29.

Management of Nasya-induced pyrexia in a patient with refractive error and migraine: a case report

Affiliations
Case Reports

Management of Nasya-induced pyrexia in a patient with refractive error and migraine: a case report

Praveen Balakrishnan et al. J Ayurveda Integr Med. 2023 Nov-Dec.

Abstract

A 23 year old young lady was admitted for Ayurveda treatments of her refractive error coupled with migraine. She was put on Shadbindu Taila Nasya, 24 drops in both her nostrils immediately the next day. Within 6 h of performing Nasya, the patient started developing pyrexia which was initially of low grade, and later, within 6 h, went on to high-grade. Nasya was suspended, and rescue Ayurveda medicines were started but had no improvement. The patient later self-medicated an antipyretic drug, and with a single dose, the high-grade pyrexia came down to normal. Naranjo adverse drug reaction probability scale recording gave a score of six, which shows that the AE could be probably due to Nasya with Shadbindu Taila. This case report adds evidence to the medical database of under-reported/poorly reported adverse effects (AE) cases of Nasya therapy. It shows that Nasya is not a 100 % complication and adverse effect free treatment, but rather has to be done with extreme caution. This case report highlights that effective Ayurveda principle based preparatory treatments are also to be done before initiating Nasya to minimize the chances of adverse effects. This case report also suggests practicing a test dose of Nasya, before initiating a high dose, so as to detect adverse events and prevent severe complications.

Keywords: Adverse effect; Ayurveda; Migraine; Nasya; Pyrexia; Refractive error; Shadbindu Taila.

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Conflict of interest statement

Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

Figures

Fig. 1
Fig. 1
Shows the plotting of temperature versus date and time chart, where date with time is on X-Axis and temperature is on Y-Axis.
Fig. 2
Fig. 2
Showing the probable etiology and pathophysiology of generation of high-grade pyrexia.

References

    1. Gupta D.P., Rajagopala M., Dhiman K.S. A clinical study on Akshitarpana and combination of Akshitarpana with Nasya therapy in Timira with special reference to myopia. Ayu. 2010 Oct;31(4):473–477. doi: 10.4103/0974-8520.82045. PMID: 22048542; PMCID: PMC3202262. - DOI - PMC - PubMed
    1. Soman A., Venkatram S., Chikkanna U., Ramakrishna K.K., Bhargav H., Mailankody P., et al. Ayurveda for management of migraine: a narrative review of clinical evidence. J Family Med Prim Care. 2022 Aug;11(8):4228–4235. doi: 10.4103/jfmpc.jfmpc_2109_21. Epub 2022 Aug 30. PMID: 36352975; PMCID: PMC9638656. - DOI - PMC - PubMed
    1. Gunes A., Demirci S., Tok L., Tok O., Koyuncuoglu H., Yurekli V.A. Refractive errors in patients with migraine headache. Semin Ophthalmol. 2016;31(5):492–494. doi: 10.3109/08820538.2014.962177. Epub 2014 Nov 20. PMID: 25412330. - DOI - PubMed
    1. Krishna Kumar V., Nair P.P., Sree Deepthi G.N., Pradeep Kumar P.P. A case report on probable short-lasting unilateral neuralgiform headache attacks with conjunctival injection and tearing following vairechanika nasya in Ménière's disease. J Ayurveda Integr Med. 2022 Apr-Jun;13(2) doi: 10.1016/j.jaim.2021.10.004. Epub 2021 Dec 27. PMID: 34969589; PMCID: PMC8728096. - DOI - PMC - PubMed
    1. Riley D.S., Barber M.S., Kienle G.S., Aronson J.K., von Schoen-Angerer T., Tugwell P., et al. CARE guidelines for case reports: explanation and elaboration document. J Clin Epidemiol. 2017 Sep;89:218–235. doi: 10.1016/j.jclinepi.2017.04.026. Epub 2017 May 18. PMID: 28529185. - DOI - PubMed

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