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Comment
. 2023 Nov;81(11):1022-1024.
doi: 10.1055/s-0043-1777009. Epub 2023 Nov 30.

Palliative care in CADASIL: diagnosis is only the first step

Affiliations
Comment

Palliative care in CADASIL: diagnosis is only the first step

Victor Aguilar-Fuentes et al. Arq Neuropsiquiatr. 2023 Nov.
No abstract available

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Conflict of interest statement

The authors have no conflict of interest to declare.

Figures

Figure 1
Figure 1
( A,B ) Fluid-attenuated inversion recovery (FLAIR) MRI scan showing extensive bilateral supratentorial leukoencephalopathy with characteristic involvement of the anterior temporal lobes (arrows) and periventricular and subcortical white matter hyperintensities (arrowheads). The cerebral cortex is not involved. ( C ) Family tree showing an autosomal dominant disease pattern. Black squares and circles represent affected relatives. An arrow indicates the patient. ( D ) Trail making test revealing profound visuospatial/executive dysfunction.

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References

    1. Nogueira R, Couto C M, Oliveira P, Martins B JAF, Montanaro V VA. Clinical and epidemiological profiles from a case series of 26 Brazilian CADASIL patients. Arq Neuropsiquiatr. 2023;81(05):417–425. doi: 10.1055/s-0042-1758756. - DOI - PMC - PubMed
    1. Hawkes M A, Wilken M, Bruno Vet al.Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) in Argentina Arq Neuropsiquiatr 20157309751–754.. Doi: 10.1590/0004-282. Doi: × 20150113 - PubMed
    1. Mizuno T, Mizuta I, Watanabe-Hosomi A, Mukai M, Koizumi T. Clinical and Genetic Aspects of CADASIL. Front Aging Neurosci. 2020;12:91. doi: 10.3389/fnagi.2020.00091. - DOI - PMC - PubMed
    1. Chabriat H, Lesnik Oberstein S. Cognition, mood and behavior in CADASIL. Cereb Circ Cogn Behav. 2022;3:100043. doi: 10.1016/j.cccb.2022.100043. - DOI - PMC - PubMed
    1. Manini A, Pantoni L. CADASIL from Bench to Bedside: Disease Models and Novel Therapeutic Approaches. Mol Neurobiol. 2021;58(06):2558–2573. doi: 10.1007/s12035-021-02282-4. - DOI - PMC - PubMed