Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2024 Jun;49(3):379-384.
doi: 10.1007/s10900-023-01307-4. Epub 2023 Nov 30.

Nocturia and Blood Pressure Elevation in Adolescents

Tasmia Promi  1 , Gulzhan Tologonova  1 , Marie-Claire Roberts  2 , Meseret Tena  3 , Sarita Dhuper  3 , Oluwatoyin Bamgbola  3 , Monique Hanono  3 , Jeffrey P Weiss  4 , Karel Everaert  5 , Tine DeBacker  6 , Thomas Monaghan  7 , Louis Salciccioli  1 , Stephen Wadowski  3 , Elka Jacobson-Dickman  3 , Jason M Lazar  8
Affiliations

Nocturia and Blood Pressure Elevation in Adolescents

Tasmia Promi et al. J Community Health. 2024 Jun.

Abstract

Nocturia has been increasingly recognized as a manifestation of various non-urological conditions including hypertension. In adults, blood pressure (BP) elevation has been identified as a robust correlate of nocturia, but such a relationship has not been studied in pediatric populations where nocturia is often attributed to hormonal, sleep, physiological or psychological disorders. Accordingly, this study aimed to determine the relationship between nocturia and BP elevation in adolescents. We prospectively studied 100 patients, aged 10-18 years, recruited from pediatric clinics at our institution. Nocturia (defined as ≥ 1 voids on voiding diary analysis) was present in 45% of the study sample (range: 1-4 voids/night). 37% of subjects self-reported awakening to urinate, and 34% of subjects had BP elevation according to age-dependent thresholds from current Pediatrics guidelines. On multivariate analyses, BP elevation was strongly associated with nocturia determined by both voiding diary (OR 26.2, 95% CI: 6.5, 106.0) and self-report. Conversely, nocturia was associated with increased odds of elevated BP by diary (26.3, 95% CI: 6.5, 106.4) and self-report (OR 8.1, 95% CI: 3.2, 20.5). In conclusion, nocturia appears to be common and is strongly associated with BP elevation in adolescents. These findings suggest that eliciting a history of nocturia holds promise as a simple method of identifying adolescents at risk for hypertension.

Keywords: Blood pressure; Early adolescents; Hypertension; Nocturia.

PubMed Disclaimer

References

    1. Hashim, H., Blanker, M. H., Drake, M. J., et al. (2019). International Continence Society (ICS) report on the terminology for nocturia and nocturnal lower urinary tract function. Neurol Urodyn, 38(2), 499–508. https://doi.org/10.1002/nau.23917 . - DOI
    1. Weiss, J. P., Monaghan, T. F., Epstein, M. R., & Lazar, J. M. (2019). Future considerations in Nocturia and Nocturnal Polyuria. Urology, 133S, 34–42. https://doi.org/10.1016/j.urology.2019.06.014 Epub 2019 Jun 22. PMID: 31233816. - DOI - PubMed
    1. Rahman, S. N., Cao, D. J., Monaghan, T. F. (2020). Phenotyping the Association between Nocturia and Hypertension: A systematic review and Meta-analysis. Journal of Urology, 101097JU0000000000001433.
    1. Victor, R. G., Li, N., Blyler, C. A., et al. (2019). Nocturia as an unrecognized symptom of uncontrolled Hypertension in Black men aged 35 to 49 years. J Am Heart Assoc, 8(5), e010794. https://doi.org/10.1161/JAHA.118.010794 PMID: 30827133; PMCID: PMC6474941. - DOI - PubMed - PMC
    1. Lazar, J. M., Posner, A., Akbar, K. (2022). Home Blood Pressure Monitoring And Nocturia In Adults. J Community Health, https://doi.org/10.1007/s10900-022-01171-8 . Epub ahead of print. PMID: 36370256.

LinkOut - more resources