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. 2023 Dec 1;133(23):e175282.
doi: 10.1172/JCI175282.

Does activating brown fat contribute to important metabolic benefits in humans? Yes!

Does activating brown fat contribute to important metabolic benefits in humans? Yes!

Aaron M Cypess. J Clin Invest. .
No abstract available

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Conflict of interest statement

Conflict of interest: The author has declared that no conflict of interest exists.

Figures

Figure 1
Figure 1. Activated BAT produces three metabolic benefits via evidence-based mechanisms.
Human BAT responds to cold, pharmacological adrenergic, and other mechanisms of stimulation by consuming glucose and fatty acids to produce mediators and generate heat via chemical uncoupling and futile cycling. Evidence established via clinical trials and mechanistic studies supports improvement to metabolism with three measurable effects: improved glucose metabolism, improved cardiovascular disease, and improved obesity.

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