Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2023 Dec 1.
doi: 10.1227/neu.0000000000002781. Online ahead of print.

Woven EndoBridge Device for Unruptured Wide-Neck Bifurcation Aneurysm: A Multicenter 5-Year Follow-up

Vittorio Semeraro  1 , Vitanio Palmisano  1 , Nicola Limbucci  2 , Simone Comelli  3 , Chiara Comelli  4 , Maria Porzia Ganimede  1 , Emilio Lozupone  5 , Michele Barone  1 , Antonio Marrazzo  1 , Andrea Paladini  1 , Giuseppina Della Malva  1 , Alessandra Briatico Vangosa  1 , Antonio Laiso  2 , Leonardo Renieri  2 , Francesco Capasso  2 , Roberto Gandini  6 , Carmine Di Stasi  1 , Maurizio Resta  1 , Salvatore Mangiafico  7 , Nicola Burdi  1
Affiliations

Woven EndoBridge Device for Unruptured Wide-Neck Bifurcation Aneurysm: A Multicenter 5-Year Follow-up

Vittorio Semeraro et al. Neurosurgery. .

Abstract

Background and objectives: This multicenter study aimed to assess the safety and efficacy of the Woven EndoBridge (WEB) device for treating unruptured wide-neck intracranial bifurcation aneurysms (WIBAs) with short-, mid-, and long-term follow-ups (FUPs).

Methods: Consecutive patients with unruptured WIBAs treated with WEB between December 2014 and January 2018 were included. Patient, aneurysm, and device characteristics were collected and analyzed retrospectively. Morbidity and mortality rates were determined by collecting intraprocedural, periprocedural, and delayed complications. Aneurysm occlusion was assessed at 1, 3, and 5 years using a 3-grade scale: complete occlusion, neck remnant, and residual aneurysm. Complete occlusion and neck remnant were considered as adequate occlusion. Patients who received re-treatment were also evaluated.

Results: The study included 104 consecutive patients (55.8% female, mean age 58.6 ± 11.8 years). Aneurysm maximum size, neck, and dome-to-neck mean were, respectively, 6.9 ± 2.1 mm, 4.5 ± 1.2 mm, and 1.4 ± 0.3 mm. One-year FUP was collected for 95 patients, and 3- and 5-year FUPs were collected for 83 patients. Adequate occlusion was observed at 1-year FUP in 90.5% (86/95), 91.6% (76/83) was observed at 3-year FUP, and 92.8% (77/83) at 5-year FUP. None of the aneurysms bled after treatment. During FUP, 6/83 patients (7.2%) were re-treated for residual aneurysm. Morbidity and mortality rates closely related to aneurysm occlusion were 0% (0/104).

Conclusion: The WEB device was safe and effective for treating unruptured WIBAs, both in short-term and long-term FUPs.

PubMed Disclaimer

References

    1. Van Rooij S, Sprengers ME, Peluso JP, et al. A systematic review and meta-analysis of Woven EndoBridge single layer for treatment of intracranial aneurysms. Interv Neuroradiol. 2020;26(4):455-460.
    1. Ding YH, Lewis DA, Kadirvel R, et al. The Woven EndoBridge: a new aneurysm occlusion device. AJNR Am J Neuroradiol. 2011;32(3):607-611.
    1. Pierot L, Barbe C, Nguyen HA, et al. Intraoperative complications of endovascular treatment of intracranial aneurysms with coiling or balloon-assisted coiling in a prospective multicenter cohort of 1088 participants: analysis of recanalization after endovascular treatment of intracranial aneurysm (ARETA) study. Radiology. 2020;295(2):381-389.
    1. Consoli A, Vignoli C, Renieri L, et al. Assisted coiling of saccular wide-necked unruptured intracranial aneurysms: stent versus balloon. J Neurointerv Surg. 2016;8(1):52-57.
    1. Yarahmadi P, Kabiri A, Bavandipour A, et al. Intra-procedural complications, success rate, and need for retreatment of endovascular treatments in anterior communicating artery aneurysms: a systematic review and meta-analysis. Neurosurg Rev. 2022;45(5):3157-3170.

LinkOut - more resources