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Review
. 2024 Mar;38(1):65-86.
doi: 10.1016/j.idc.2023.11.001. Epub 2023 Nov 30.

Is Zero Ventilator-Associated Pneumonia Achievable? Updated Practical Approaches to Ventilator-Associated Pneumonia Prevention

Cristina Vazquez Guillamet  1 , Marin H Kollef  2
Affiliations
Review

Is Zero Ventilator-Associated Pneumonia Achievable? Updated Practical Approaches to Ventilator-Associated Pneumonia Prevention

Cristina Vazquez Guillamet et al. Infect Dis Clin North Am. 2024 Mar.

Abstract

Ventilator-associated pneumonia (VAP) remains a significant clinical entity with reported incidence rates of 7% to 15%. Given the considerable adverse consequences associated with this infection, VAP prevention became a core measure required in most US hospitals. Many institutions took pride in implementing effective VAP prevention bundles that combined at least head of bed elevation, hand hygiene, chlorhexidine oral care, and subglottic drainage. Spontaneous breathing and awakening trials have also consistently been shown to shorten the duration of mechanical ventilation and secondarily reduce the occurrence of VAP.

Keywords: Antimicrobial resistance; Compliance; Effectiveness; Prevention bundle; Ventilator-associated pneumonia.

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Conflict of interest statement

Disclosures Dr M.H. Kollef’s efforts were supported by the Barnes-Jewish Hospital Foundation, United States. Dr C.V. Guillamet has no conflicts of interest to report.

MeSH terms