Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2024 May;36(5):e24026.
doi: 10.1002/ajhb.24026. Epub 2023 Dec 2.

Hypertensive disorders of pregnancy in Western Brazilian Amazon: Associated factors and neonatal outcomes

Ana Alice de Araújo Damasceno  1   2 , Alicia Matijasevich  3 , Paola Soledad Mosquera  1 , Maíra Barreto Malta  4 , Marly Augusto Cardoso  4 ; MINA‐Brazil Study Group
Collaborators, Affiliations

Hypertensive disorders of pregnancy in Western Brazilian Amazon: Associated factors and neonatal outcomes

Ana Alice de Araújo Damasceno et al. Am J Hum Biol. 2024 May.

Abstract

Objective: Hypertensive disorders of pregnancy (HDP) are responsible for several maternal and fetal complications. This study investigated the occurrence of HDP, associated factors, and neonatal complications in women living in the Western Brazilian Amazon.

Methods: This is a population-based cross-sectional study with 1521 mother-child pairs enrolled in the Maternal and Child Health and Nutrition in Acre birth cohort (MINA-Brazil study). All parturients with HDP (registered in the medical records) were identified. Crude and adjusted prevalence ratios were calculated in Poisson regression models with robust variance.

Results: The prevalence of HDP was 11.0% (95% CI: 9.5-12.7). Factors associated with the prevalence of HDP were maternal age ≥ 35 years (PR: 1.9; 95% CI: 1.3-3.0), primigravida status (PR: 2.0; 95% CI: 1.5-2.7), pre-pregnancy obesity (PR: 2.7; 95% CI: 1.9-4.0), higher gestational weight gain (highest quartile RP: 2.5; 95% CI: 1.6-3.8), chronic hypertension (RP: 3.6; 95% CI: 2.7-4.9), and diabetes in pregnancy (RP: 1.9; 95% CI: 1.1-3.2). HDP was associated with risk for caesarean delivery (PR: 1.8; 95% CI: 1.6-2.0) and prematurity (PR: 2.0; 95% CI: 1.3-3.2). Gestational malaria was not associated with HDP in Amazonian pregnant women.

Conclusions: Evaluating risk factors before pregnancy and during the prenatal period is essential for reducing adverse maternal and neonatal outcomes.

PubMed Disclaimer

References

REFERENCES

    1. ACOG. (2013). Hypertension in pregnancy. American College of Obstetricians and Gynecologists.
    1. Bacelar, E. B., Costa, M. C. O., Gama, S. G. N. D., Amaral, M. T. R., & Almeida, A. H. D. V. D. (2017). Factors associated with specific hypertensive gestation syndrome (SHGS) in postpartum adolescent and young adult mothers in the northeast of Brazil: A multiple analysis of hierarchical models. Revista Brasileira de Saúde Materno Infantil, 17, 673–681. https://doi.org/10.1590/1806-93042017000400004
    1. Bilano, V. L., Ota, E., Ganchimeg, T., Mori, R., & Souza, J. P. (2014). Risk factors of pre‐eclampsia/eclampsia and its adverse outcomes in low‐ and middle‐income countries: A WHO secondary analysis. PLoS One, 9(3), e91198. https://doi.org/10.1371/journal.pone.0091198
    1. Brasil. Ministério da Saúde. (2021). DATASUS—Tecnologia da informação a serviço do SUS. In Brasília: Ministério da Saúde. acesso em 11 dez http://tabnet.datasus.gov.br/cgi/deftohtm.exe?siab/cnv/SIABSac.def
    1. Brasil Ministério da Saúde. Secretaria de Atenção Primária à Saúde. Departamento de Ações Programáticas. (2022). Manual de gestação de alto risco [recurso eletrônico. Brasília]. Ministério da Saúde, Brasil. https://portaldeboaspraticas.iff.fiocruz.br/atencaomulher/manual‐de‐gest...

Publication types

LinkOut - more resources