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Review
. 2023 Oct;32(5):151338.
doi: 10.1016/j.sempedsurg.2023.151338. Epub 2023 Nov 21.

Critical elements of pediatric neuroblastoma surgery

Shahab A Shaffiey  1 , Hau D Le  2 , Emily Christison-Lagay  3 , Elizabeth A Fialkowski  4 , Jennifer H Aldrink  5 , Christa N Grant  6 , Joshua N Honeyman  7 , Kevin C Janek  8 , Mary Beth Madonna  9 , Daniel S Rhee  10 , Jed G Nuchtern  11 , Erika A Newman  12 , Michael P LaQuaglia  7 , Andrew M Davidoff  13 , Robert C Shamberger  14 , Marcus M Malek  15
Affiliations
Review

Critical elements of pediatric neuroblastoma surgery

Shahab A Shaffiey et al. Semin Pediatr Surg. 2023 Oct.

Abstract

Neuroblastoma (NB) is the most common solid extracranial malignancy of childhood with an incidence of 1 per 100,000 in the United States compromising approximately 10 % of childhood cancer. Unfortunately, patients with high-risk NG continue to have long-term survival less than 50 %. Both Children's Oncology Group and the International Society of Paediatric Oncology have demonstrated the important role of surgery in the treatment of high-risk NB. Herein, we compose the results of an extensive literature review as well as expert opinion from leaders in pediatric surgical oncology, to present the critical elements of effective surgery for high-risk neuroblastoma.

Keywords: Complete Macroscopic Excision; Gross total resection; Neuroblastoma.

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