doi: 10.1007/BF00273833.
Single cell translocations in couples with multiple spontaneous abortions
- PMID: 3804328
- DOI: 10.1007/BF00273833
Item in Clipboard
Single cell translocations in couples with multiple spontaneous abortions
Hum Genet.
1987 Jan.
Abstract
Single cell translocations have been previously reported to occur in normal lymphocyte cultures. Comparison of the frequency of these in 140 individuals referred for a history of multiple miscarriages and 415 individuals referred for a history of multiple miscarriages and 415 individuals referred for other reasons showed a significantly greater number of single cell translocations in the former group. This group also had a significantly greater number of other types of single cell structural abnormalities. Increased chromosome instability, chromosome mosaicism, residual fetal trophoblasts, and immunological differences are discussed in considering the possible etiology.
Similar articles
-
Chromosome anomalies in 136 couples with a history of recurrent abortions.Hum Genet. 1983;65(1):48-52. doi: 10.1007/BF00285027. Hum Genet. 1983. PMID: 6642507
-
Chromosome translocations in couples with multiple spontaneous abortions.Am J Hum Genet. 1982 May;34(3):507-13. Am J Hum Genet. 1982. PMID: 7081226 Free PMC article.
-
Chromosomal findings in 164 couples with repeated spontaneous abortions: with special consideration to prior reproductive history.Hum Genet. 1983;63(1):28-34. doi: 10.1007/BF00285393. Hum Genet. 1983. PMID: 6832778
-
[Cytogenetic study of peripheral lymphocyte culture in couples with habitual abortion].Zentralbl Gynakol. 1991;113(19):1046-52, 1057-8. Zentralbl Gynakol. 1991. PMID: 1962519 Review. German.
-
Balanced translocation karyotypes in patients with repetitive abortion. Case study and literature review.Am J Obstet Gynecol. 1982 Sep 15;144(2):229-33. doi: 10.1016/0002-9378(82)90633-0. Am J Obstet Gynecol. 1982. PMID: 7051833 Review.
Cited by
-
Cytogenetic Investigation of Infertile Patients in Hungary: A 10-Year Retrospective Study.Genes (Basel). 2022 Nov 10;13(11):2086. doi: 10.3390/genes13112086. Genes (Basel). 2022. PMID: 36360324 Free PMC article.
-
On the variable effect of mosaic normal/balanced chromosomal rearrangements in man.J Med Genet. 1990 Aug;27(8):505-7. doi: 10.1136/jmg.27.8.505. J Med Genet. 1990. PMID: 2213843 Free PMC article.