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. 1986 Nov;19(3-4):279-88.
doi: 10.1016/0020-7101(86)90070-x.

Calculation of Hill slopes predicted by the four ligand exponential model for a regulatory enzyme

S Ainsworth, N Rhodes

Calculation of Hill slopes predicted by the four ligand exponential model for a regulatory enzyme

S Ainsworth et al. Int J Biomed Comput. 1986 Nov.

Abstract

The Hill slopes predicted by the exponential model for a regulatory enzyme have been calculated by two separate methods, one analytical and the other numerical. Both methods are applicable to enzymes with up to 4 substrates; alternatively, one substrate may be replaced by an effector. The maximum or minimum Hill slope can also be ascertained by an extension of the analytical method.

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