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Comparative Study
. 1979 Apr;15(4):518-21.
doi: 10.1128/AAC.15.4.518.

Thienamycin: new beta-lactam antibiotic with potent broad-spectrum activity

S S Weaver, G P Bodey, B M LeBlanc
Comparative Study

Thienamycin: new beta-lactam antibiotic with potent broad-spectrum activity

S S Weaver et al. Antimicrob Agents Chemother. 1979 Apr.

Abstract

Thienamycin, a new beta-lactam antibiotic, exhibited potent, broad-spectrum activity in vitro against gram-negative bacilli and gram-positive cocci, including many isolates resistant to currently available antibiotics. All isolates were inhibited at concentrations less than or equal to 25 mug/ml, with the exception of 12% of isolates of Enterobacter spp. and 3% of isolates of Serratia marcescens. Its activity decreased with an increase in inoculum concentration of from 10(5) to 10(7) cells per ml.

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References

    1. Antimicrob Agents Chemother. 1977 Jan;11(1):74-9 - PubMed
    1. Antimicrob Agents Chemother. 1978 Jul;14(1):78-87 - PubMed
    1. Antimicrob Agents Chemother. 1977 May;11(5):865-70 - PubMed
    1. Antimicrob Agents Chemother. 1978 Sep;14(3):436-8 - PubMed
    1. Antimicrob Agents Chemother. 1978 Jan;13(1):14-8 - PubMed

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