Early-life microbiota as a baby metabolic guardian
- PMID: 38056427
- DOI: 10.1016/j.cmet.2023.11.008
Early-life microbiota as a baby metabolic guardian
Abstract
Early-life microbiota have a crucial role in healthy development. Antibiotics, on the other hand, can disrupt this beneficial interaction and have been linked to increased adiposity in children. Shelton and collaborators went deeper into the mechanism by which microbiota protect against lipid metabolic dysfunction and diet-induced obesity. The results highlight the long-term metabolic risk of early antibiotic exposure.
Copyright © 2023 Elsevier Inc. All rights reserved.
Conflict of interest statement
Declaration of interests M.N. is co-founder and member of the Scientific Advisory Board of Caelus Pharmaceuticals and Advanced Microbiome interventions, the Netherlands. However, none of these are relevant for the current paper.
Comment on
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An early-life microbiota metabolite protects against obesity by regulating intestinal lipid metabolism.Cell Host Microbe. 2023 Oct 11;31(10):1604-1619.e10. doi: 10.1016/j.chom.2023.09.002. Epub 2023 Oct 3. Cell Host Microbe. 2023. PMID: 37794592 Free PMC article.
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