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1 Department of Medicine, Boston Medical Center, Boston, MA, USA.
2 Department of Medicine, Section of Nephrology, Boston University Chobanian & Avedisian School of Medicine, Boston, MA, USA. Electronic address: ashverma@bu.edu.
1 Department of Medicine, Boston Medical Center, Boston, MA, USA.
2 Department of Medicine, Section of Nephrology, Boston University Chobanian & Avedisian School of Medicine, Boston, MA, USA. Electronic address: ashverma@bu.edu.
In a recent Presidential Advisory report, the American Heart Association (AHA) defined cardiovascular-kidney-metabolic (CKM) syndrome as a spectrum of pathology associated with dysfunctional or excess adiposity and leading to adverse cardiovascular outcomes. Implementing the guidelines set forth by the AHA has the potential to improve population-wide CKM health.
Ndumele CE, Rangaswami J, Chow SL, Neeland IJ, Tuttle KR, Khan SS, Coresh J, Mathew RO, Baker-Smith CM, Carnethon MR, et al. (2023). Cardiovascular-kidney-metabolic health: a Presidential Advisory from the American Heart Association. Circulation. 10.1161/CIR.0000000000001184.
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Koenen M, Hill MA, Cohen P, and Sowers JR (2021). Obesity, adipose tissue and vascular dysfunction. Circ. Res 128, 951–968. 10.1161/CIRCRESAHA.121.318093.
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Jia G, Aroor AR, and Sowers JR (2017). The role of mineralocorticoid receptor signaling in the cross-talk between adipose tissue and the vascular wall. Cardiovasc. Res 113, 1055–1063. 10.1093/cvr/cvx097.
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Morales J, and Handelsman Y (2023). Cardiovascular outcomes in patients with diabetes and kidney disease: JACC review topic of the week. J. Am. Coll. Cardiol 82, 161–170. 10.1016/j.jacc.2023.04.052.
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Karagiannis T, Bekiari E, and Tsapas A (2023). Socioeconomic aspects of incretin-based therapy. Diabetologia 66, 1859–1868. 10.1007/s00125-023-05962-z.
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