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. 2023 Dec 6;23(1):1197.
doi: 10.1186/s12885-023-11666-9.

A population-based analysis of hematological malignancies from a French-West-Indies cancer registry's data (2009-2018)

Rémi Houpert  1 , Thierry Almont  2 , Rostom Belahreche  3 , Mamadi Faro  3 , Jennie Okouango  3 , Mylène Vestris  4 , Jonathan Macni  4 , Olivier Pierre-Louis  5 , Christelle Montabord  2 , Murielle Beaubrun-Renard  4 , Naby Soumah  3 , Martial Boisseau  3 , Jacqueline Véronique-Baudin  2 , Clarisse Joachim  6
Affiliations

A population-based analysis of hematological malignancies from a French-West-Indies cancer registry's data (2009-2018)

Rémi Houpert et al. BMC Cancer. .

Abstract

Background: A worldwide increased incidence of HM has been marked in recent decades. Therefore, to update epidemiological characteristics of HM in a French West Indies territory, we have performed analysis through Martinique's population-based cancer registry database.

Methods: We included cancer case data, from 2009-2018, coded in strict compliance with international standards set by International Agency for Research on Cancer. We calculated standardized incidence rates, cumulative rate (ages 0-74), and temporal trends for cases and deaths using the global population standard, by sex and five age group. Mortality rates were obtained from the French Epidemiology Center on Medical Causes of Death (CépiDc).

Results: One thousand forty seven new cases and 674 deaths from HM were recorded, of which 501 MM (47.8%), 377 LMNH (36%), 123 LAM (11.8%), and 46 LH (4.4%) were reported in both sexes. MM is one of the hematological malignancies with the highest incidence in Martinique among men. Temporal trends of incidence rates for all HM decreased overall in both sexes, except for MM in men. There is significant variability in mortality rates for both sexes. In addition, over the period, the temporal trends of mortality rates for all HMs has decreased overall. Gender-specific rates, between 2009 and 2018, showed that all lymphoid HM have a multimodal distribution curve that increased with age.

Conclusions: Characteristics of HM in Martinique over the reporting periods differ from mainland France. Higher incidences have been observed, particularly for MM, and non-significant sub-mortality is observed compared to mainland France. Moreover, temporal distribution of mortality and incidence trends had decreased over the reporting periods except for MM. Our results showed similarities with African-Americans groups in United States and in particular an equivalence in the frequency distribution of diagnosed HM. However, SMR remains lower compared to US black ethnic groups. Our results contributed to expanding knowledge on the epidemiology of HM with Caribbean data.

Keywords: Caribbean; Epidemiology; Hematological Malignancies; Lymphoma; Multiple Myeloma; Non-Hodgkin Lymphoma.

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Conflict of interest statement

The authors declare no competing interests.

Figures

Fig. 1
Fig. 1
Distribution of Hematological Malignancies according to cancer cases in Martinique, by sex (2009–2018)
Fig. 2
Fig. 2
Standardized incidence for all Hematological Malignacies by sex, in Martinique (2009–2018)
Fig. 3
Fig. 3
Age and Sex-specific Structure rate for all Hematological Malignancies in Martinique (2009–2018)
Fig. 4
Fig. 4
Temporal Trends of standardized incidence and mortality rates for all Hematological Maligancies by sex, in Martinique (2009-2018)
See this image and copyright information in PMC

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