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. 2023 Dec 7;18(12):e0294331.
doi: 10.1371/journal.pone.0294331. eCollection 2023.

Online psychoeducation and digital assessments as a first step of treatment for borderline personality disorder: A protocol for a pilot randomized controlled trial

Lois W Choi-Kain  1   2 , Grace E Murray  3 , Julia Jurist  1 , Boyu Ren  1   2 , Laura Germine  1   2
Affiliations

Online psychoeducation and digital assessments as a first step of treatment for borderline personality disorder: A protocol for a pilot randomized controlled trial

Lois W Choi-Kain et al. PLoS One. .

Abstract

Background: Treatment trials for borderline personality disorder (BPD) have consistently demonstrated that approaches that are diagnostically tailored are superior to those which are not. Currently, gold standard treatments for BPD are highly intensive, lengthy, and specialized, leading to a critical gap between the supply and demand of effective, evidence-based treatment for patients who receive a diagnosis of BPD. Psychoeducation, which is a common component of most treatments known to be effective, is a low-cost, low-burden intervention proven to relieve symptoms. The present study builds on psychoeducation research, assessing online video prescriptions as a means of disseminating information patients need to know about their diagnosis and care.

Methods: This article presents the study protocol for a safety, feasibility, and preliminary efficacy trial of psychoeducational video prescriptions and online assessment with feedback for newly diagnosed individuals with BPD. We aim to recruit 100 adults recently diagnosed with BPD to be randomly assigned to receive videos about BPD or videos about non-BPD mental health topics that are matched in length in the first step of the study. All participants will complete daily surveys about their emotions, interpersonal interactions, and behaviors, as well as self-report assessments and cognitive tests at 4 different time points. Half of the participants in the intervention group will receive feedback on their symptom ratings and cognitive test performance to assess whether there is incremental value in tailoring this online set of interventions with individualized feedback unique to each participant. This study aims to assess the effects of BPD-focused psychoeducational videos with and without personalized feedback, on BPD and depressive symptom severity as well as core mechanisms of the disorder such as loneliness, rejection sensitivity, cognitive control difficulties, and self-clarity. Results will inform efforts to progress to a larger, more definitive trial.

Trial registration: Clinical trials registration: The protocol is registered with ClinicalTrials.gov NCT05358925.

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Conflict of interest statement

The authors have declared that no competing interests exist.

Figures

Fig 1
Fig 1. Schedule of enrolment, interventions, and assessments.
-t1 = Timepoint A (baseline); t1 = Timepoint B; t2 = Timepoint C; tx = Timepoint D.
Fig 2
Fig 2. Study schema.
In the Study Schema, “A” corresponds to Baseline, “B” to Time 2, “C” to Time 3, and “D” to Follow-up.
See this image and copyright information in PMC

References

    1. Choi-Kain LW, Sahin Z, Traynor J. Borderline personality disorder: Updates in a postpandemic world. Focus (Am Psychiatr Publ). 2022. Oct;20(4):337–352. doi: 10.1176/appi.focus.20220057 - DOI - PMC - PubMed
    1. Cristea IA, Gentili C, Cotet CD, Palomba D, Barbui C, Cuijpers P. Efficacy of psychotherapies for borderline personality disorder: A systematic review and meta-analysis. JAMA Psychiatry. 2017;74(4):319–328. doi: 10.1001/jamapsychiatry.2016.4287 - DOI - PubMed
    1. Iliakis EA, Sonley AK, Ilagan GS, Choi-Kain LW. Treatment of borderline personality disorder: Is supply adequate to meet public health needs?. Psychiatr Serv. 2019;70(9):772–81. doi: 10.1176/appi.ps.201900073 - DOI - PubMed
    1. McMain SF, Chapman AL, Kuo JR, Dixon-Gordon KL, Guimond TH, Labrish C, et al. The Effectiveness of 6 versus 12 Months of Dialectical Behavior Therapy for Borderline Personality Disorder: A Noninferiority Randomized Clinical Trial. Psychother Psychosom. 2022;91(6):382–397. doi: 10.1159/000525102 - DOI - PubMed
    1. Juul S, Simonsen S, Poulsen S, Lunn S, Sørensen P, Bateman A, et al. Detailed statistical analysis plan for the short-term versus long-term mentalisation-based therapy for outpatients with subthreshold or diagnosed borderline personality disorder randomised clinical trial (MBT-RCT). Trials. 2021. Jul 28;22(1):497. doi: 10.1186/s13063-021-05450-y - DOI - PMC - PubMed

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