Measles seroprevalence in adolescents and young adults living with HIV and response to MMR booster in seronegative ones
- PMID: 38061022
- DOI: 10.1097/QAD.0000000000003720
Measles seroprevalence in adolescents and young adults living with HIV and response to MMR booster in seronegative ones
Abstract
Objective: The study analyzed people with HIV (PWH) measles seroprevalence and response to MMR booster given to seronegative individuals.
Design: A prospective cohort study with four groups: vertically (v-HIV), horizontally infected (h-HIV) individuals, and two control groups. An MMR booster was offered to seronegative individuals.
Results: Measles seropositivity and IgG antibodies were significantly lower in v-HIV than in the other groups. All measles seronegative patients responded to booster.
Conclusion: An MMR booster must be sought during adolescence in vertically PWH.
Copyright © 2023 Wolters Kluwer Health, Inc. All rights reserved.
References
-
- De Moraes-Pinto MI, Almeida AC, Kenji G, Filgueiras TE, Tobias W, Santos AM, et al. Placental transfer and maternally acquired neonatal IgG immunity in human immunodeficiency virus infection . J Infect Dis 1996; 173:1077–1084.
-
- World Health Organization - Immunization, Vaccines and Biologicals. The immunological basis for immunization series. Module 7: Measles. 2009. http://apps.who.int/iris/bitstream/handle/10665/44038/9789241597555_eng.... . [Accessed 9 September 2022]
-
- Schenk J, Abrams S, Theeten H, Van Damme P, Beutels P, Hens N. Immunogenicity and persistence of trivalent measles, mumps, and rubella vaccines: a systematic review and meta-analysis . Lancet Infect Dis 2021; 21:286–295.
-
- Succi RCM, Krauss MR, Harris R, Machado DM, de Moraes-Pinto MI, Mussi-Pinhata MM, et al. for the NISDI Pediatric Study Group 2012. Immunity following childhood vaccinations in perinatally HIV-exposed children with and without HIV infection in Latin America . Pediatr Infect Dis J 2018; 37:304–309.
-
- Pensieroso S, Cagigi A, Palma P, Nilsson A, Capponi C, Freda E, et al. Timing of HAART defines the integrity of memory B cells and the longevity of humoral responses in HIV-1 vertically-infected children . Proc Natl Acad Sci U S A 2009; 106:7939–7944.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Medical
