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Case Reports
. 2023 Nov;35(Suppl 2):S187-S190.
doi: 10.5021/ad.21.186.

Drug Reaction with Eosinophilia and Systemic Symptom Syndrome Due to Everolimus: A Case Report

Mehmet Erdem Çakmak  1
Affiliations
Case Reports

Drug Reaction with Eosinophilia and Systemic Symptom Syndrome Due to Everolimus: A Case Report

Mehmet Erdem Çakmak. Ann Dermatol. 2023 Nov.

Abstract

Drug reaction with eosinophilia and systemic symptom (DRESS) is a life-threatening drug hypersensitivity reaction that is characterized by skin rash, hematological abnormalities (eosinophilia, atypical lymphocytosis), lymphadenopathy, and internal organ involvement (liver, kidneys, and lung). Many drugs may cause DRESS syndrome, the most frequently reported of which are antiepileptics and allopurinol. In this case report, a patient who developed DRESS syndrome due to everolimus was presented herein.

Keywords: Drug hypersensitivity; Eosinophilia; Everolimus; Hypersensitivity.

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Conflict of interest statement

The author has nothing to disclose.

Figures

Fig. 1
Fig. 1. The patient was admitted to our allergy clinic 10 days after everolimus treatment was discontinued, and the patient’s maculopapular skin rashes had partially resolved.
Fig. 2
Fig. 2. Right lung middle lobe and lower lobe peripheral infiltrations on thorax computed tomography.
See this image and copyright information in PMC

References

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