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Case Reports
. 2023 Nov;35(Suppl 2):S239-S242.
doi: 10.5021/ad.21.165.

Pilomatricoma on the Sole Following Wart Treatment

Na Young Kim  1 , You Jin Jung  1 , Ki Yeon Kim  1 , Joo Yeon Ko  1 , Young Suck Ro  1 , Jeong Eun Kim  2
Affiliations
Case Reports

Pilomatricoma on the Sole Following Wart Treatment

Na Young Kim et al. Ann Dermatol. 2023 Nov.

Abstract

Pilomatricoma is a benign skin tumor that arises from hair follicle stem cells. It typically presents in the facial region and rarely involves the palms and soles. A 15-year-old boy presented with a solitary tender nodule on the left sole. He had a history of plantar warts on the same site and had received multiple treatments including cryotherapy and intralesional bleomycin injection for nine months. Excisional biopsy was performed, and the specimen showed a well-demarcated mass in the deep dermis with basaloid cells undergoing abrupt keratinization. Ghost cells were seen with calcification. Based on these findings, he was diagnosed with pilomatricoma on the sole. We report a case of pilomatricoma, which developed on a site without hair follicles.

Keywords: Pilomatricoma; Trauma; Warts.

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Conflict of interest statement

The authors have nothing to disclose.

Figures

Fig. 1
Fig. 1. An 8-mm-sized solitary tender nodule was located on the left forefoot.
Fig. 2
Fig. 2. (A) The biopsy specimen showed a well-circumscribed tumor from deep dermis to subcutaneous layer (H&E, scanning view). (B) It mainly showed eosinophilic keratinization with some inflammatory cells (H&E, ×100). (C) The abrupt trichilemmal keratinization from basaloid cells into shadow cells was observed. The basaloid nests resemble the matrix cells in hair follicle (H&E, ×200). (D) The ghost cells with calcifications were seen. The stroma contains multinucleated giant cells reacting to tumoral keratin (H&E, ×400).
Fig. 3
Fig. 3. The patient experienced no recurrence for about three years after the excision.
See this image and copyright information in PMC

References

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