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Case Reports
. 2023 Dec 7;16(12):e254701.
doi: 10.1136/bcr-2023-254701.

Digital ischaemia as a presenting feature in metastatic ovarian cancer

Jonathan Harry Miller  1   2 , Peter Merry  3
Affiliations
Case Reports

Digital ischaemia as a presenting feature in metastatic ovarian cancer

Jonathan Harry Miller et al. BMJ Case Rep. .

Abstract

A woman in her 50s presented with acute pain and discolouration in the fingertips of both hands, without other features of connective tissue disease. The history was otherwise significant for abdominal bloating, altered bowel habit, urinary urgency and fatigue. Inflammatory markers, antinuclear antibodies, serum protein electrophoresis and complement levels were all normal. The tumour marker CA125 was significantly elevated, prompting a CT abdomen and pelvis, which revealed a large right-sided adnexal mass with multiple enhancing peritoneal and omental nodules and moderate ascites, suggestive of disseminated primary ovarian cancer.Digital ischaemia (DI) can be associated with cancer in up to 15% of cases. An underlying cancer should be suspected in patients presenting with new or worsening symptoms of DI. Prompt treatment with anticancer therapies can achieve complete resolution of DI.

Keywords: Connective tissue disease; Gynecological cancer; Vasculitis.

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Conflict of interest statement

Competing interests: None declared.

Figures

Figure 1
Figure 1
Ten-digit ischaemia at initial presentation.
See this image and copyright information in PMC

References

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