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. 2023 Dec;28(49):2300606.
doi: 10.2807/1560-7917.ES.2023.28.49.2300606.

Early lessons from the implementation of universal respiratory syncytial virus prophylaxis in infants with long-acting monoclonal antibodies, Galicia, Spain, September and October 2023

Federico Martinón-Torres  1   2   3   4 , Susana Mirás-Carballal  5 , Carmen Durán-Parrondo  5
Affiliations

Early lessons from the implementation of universal respiratory syncytial virus prophylaxis in infants with long-acting monoclonal antibodies, Galicia, Spain, September and October 2023

Federico Martinón-Torres et al. Euro Surveill. 2023 Dec.

Abstract

A monoclonal antibody for universal respiratory syncytial virus prophylaxis in infants has recently been licensed. We share our experiences of integrating nirsevimab into the regional immunisation programme in Galicia, Spain. After a 3-week hospital-based immunisation campaign with flexible individualised appointments and educational activities, nirsevimab uptake was 97.5% in the high-risk group, 81.4% in the catch-up group and 92.6% in infants born during the campaign. This successful implementation strategy can serve as a model and may inform other countries' programmatic deliberations.

Keywords: Respiratory Syncytial Virus; immunoprophylaxis; implementation; long-acting monoclonal antibodies; nirsevimab.

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Conflict of interest statement

Conflict of interest: Federico Martinón-Torres has acted as principal investigator in randomised controlled trials of Ablynx, Abbot, Seqirus, Sanofi Pasteur MSD, Sanofi Pasteur, Cubist, Wyeth, Merck, Pfizer, Roche, Regeneron, Jansen, Medimmune, Novavax, Novartis and GSK, with honoraria paid to his institution. Federico Martinon-Torres reports a relationship with GSK Vaccines SRL that includes: consulting or advisory. Federico Martinon-Torres reports a relationship with Pfizer Inc that includes: consulting or advisory. Federico Martinon-Torres reports a relationship with Sanofi Pasteur Inc that includes: consulting or advisory. Federico Martinon-Torres reports a relationship with Janssen Pharmaceuticals Inc that includes: consulting or advisory. Federico Martinon-Torres reports a relationship with MSD that includes: consulting or advisory. Federico Martinon-Torres reports a relationship with Seqirus Pty Ltd that includes: consulting or advisory. The remaining authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

References

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