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Comment
. 2023 Dec 7;83(23):4199-4201.
doi: 10.1016/j.molcel.2023.10.044.

Unlocking the EGFR-mediated epitranscriptome: A pathway to novel therapies

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Unlocking the EGFR-mediated epitranscriptome: A pathway to novel therapies

Jovanka Gencel-Augusto et al. Mol Cell. .
Free article

Abstract

In this issue, Lv et al.1 explore EGFR-driven epitranscriptomic reprogramming in glioblastoma, revealing the pivotal role of the EGFR-ALKBH5-GCLM axis in ferroptosis protection. Their findings offer mechanistic insight and therapeutic strategies involving novel combination targets to enhance tumor responses.

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Conflict of interest statement

Declaration of interests The authors declare no conflicts of interest.

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