Liquid biopsy: from concept to clinical application
- PMID: 38066040
- PMCID: PMC10709452
- DOI: 10.1038/s41598-023-48501-x
Liquid biopsy: from concept to clinical application
Abstract
The diagnosis and treatment of cancer presents a physical and mental burden to the patient, often involving diagnostic biopsies and surgeries or chemotherapeutic approaches with severe side-effects. Advances which enable early detection of cancer and close monitoring of the disease course without invasive procedures, and which can underpin a tailored approach to treatment, can therefore make a big difference to the quality of life of patients. Liquid biopsies can be used to access tumor cells and tumor DNA circulating in the blood. Monitoring these species can provide a minimally invasive and repeatable means to detect cancer, or gain information about its response to treatment.
Conflict of interest statement
CAP received honoraria from Menarini; DM does not have any COI to disclose. JL does not have any COI to disclose.
References
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- Alix-Panabieres C, Pantel K. Liquid biopsy: From discovery to clinical application. Cancer Discov. 2021;11:858–873. doi: 10.1158/2159-8290.CD-20-1311. - DOI - PubMed
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