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Review
. 2023 Dec 8;2023(1):254-258.
doi: 10.1182/hematology.2023000478.

How to manage ITP with life-threatening bleeding

Jean M Connors  1 , Steven Fein  2
Affiliations
Review

How to manage ITP with life-threatening bleeding

Jean M Connors et al. Hematology Am Soc Hematol Educ Program. .

Abstract

While immune thrombocytopenia often presents with mild bleeding manifestations or surprising findings of thrombocytopenia on routine complete blood counts in patients without symptoms, some patients can present with new thrombocytopenia and life-threatening bleeding. Emergent assessment and treatment are needed to prevent substantial morbidity and even mortality. These patients present to the emergency room with bleeding, and hematologists are subsequently consulted. Understanding the approach to making the diagnosis and excluding other life-threatening illnesses is essential, as is rapid initiation of treatment in the bleeding patient even when the diagnosis of immune- mediated thrombocytopenia is tentative. Using a case-based format, we review how to approach and treat patients presenting with new thrombocytopenia and bleeding.

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Conflict of interest statement

Steven Fein: speakers bureau for Amgen and Sobi. Jean Connors: Nothing to disclose.

Figures

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Graphical abstract
See this image and copyright information in PMC

References

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