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Review
. 2023 Nov 22;24(23):16614.
doi: 10.3390/ijms242316614.

Bioactive Compounds and Their Influence on Postnatal Neurogenesis

Simona Mattova  1 , Patrik Simko  1 , Nicol Urbanska  1 , Terezia Kiskova  1
Affiliations
Review

Bioactive Compounds and Their Influence on Postnatal Neurogenesis

Simona Mattova et al. Int J Mol Sci. .

Abstract

Since postnatal neurogenesis was revealed to have significant implications for cognition and neurological health, researchers have been increasingly exploring the impact of natural compounds on this process, aiming to uncover strategies for enhancing brain plasticity. This review provides an overview of postnatal neurogenesis, neurogenic zones, and disorders characterized by suppressed neurogenesis and neurogenesis-stimulating bioactive compounds. Examining recent studies, this review underscores the multifaceted effects of natural compounds on postnatal neurogenesis. In essence, understanding the interplay between postnatal neurogenesis and natural compounds could bring novel insights into brain health interventions. Exploiting the therapeutic abilities of these compounds may unlock innovative approaches to enhance cognitive function, mitigate neurodegenerative diseases, and promote overall brain well-being.

Keywords: EGCG; atranorin; bioactive compounds; melatonin; neurodegenerative disorders; postnatal neurogenesis; resveratrol.

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
The application of biologically active compounds has an impact on molecular mechanisms involved during postnatal neurogenesis not only in healthy brains but also during various neurological diseases. Created with BioRender.com.
See this image and copyright information in PMC

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