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Case Reports
. 2023 Dec;17(12):1368-1371.
doi: 10.1111/crj.13724. Epub 2023 Dec 10.

A rare case of hepatoid adenocarcinoma of the lung

Xuejian Sun  1   2 , Jialin Liu  1   2 , Ting Hu  1   2 , Yefan Wu  1   2 , Hao Zhang  1   2
Affiliations
Case Reports

A rare case of hepatoid adenocarcinoma of the lung

Xuejian Sun et al. Clin Respir J. 2023 Dec.

Abstract

Hepatoid adenocarcinoma of the lung is a special type of primary origin in the lung with obvious pathological features and short survival time. However, standard treatment guidelines have not yet been established. Herein, we report a case of hepatoid adenocarcinoma with the primary lesion located in the left upper lung. The tumour size was reduced after four cycles of combined therapy. Subsequent postoperative pathology confirmed complete remission.

Keywords: HAL; hepatoid adenocarcinoma; hepatoid adenocarcinoma of the lung; rare lung cancer.

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Conflict of interest statement

The authors declare no conflict of interest in association with this report.

Figures

FIGURE 1
FIGURE 1
(A,B) Non‐contrast chest computed tomography (CT) scan revealed a soft tissue in the left upper lobe, measuring 47 × 39 mm in size. (C–E) Three months later, contrast‐enhanced CT showing the mass appeared inhomogeneous enhancement, which was larger than before, measuring 91 × 61 mm in size.
FIGURE 2
FIGURE 2
Histological features. (A,B) Haematoxylin and eosin (HE) indicated that the tumour tissue was arranged in irregular glandular tubular, sieve and nest‐like arrangement. The nuclear atypia was obvious, and the cytoplasm in some areas was clear, showing infiltrative growth. Hepatocyte (+) (C), SALL4 (+) (D), Syn (+) (E), TTF‐1(+) (F).
See this image and copyright information in PMC

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