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Review
. 2024 Jan;34(1):e2493.
doi: 10.1002/rmv.2493. Epub 2023 Dec 11.

Role of the VEGF in virus-associated cancers

Shaian Tavakolian  1   2 , Seidamir Pasha Tabaeian  3   4 , Abolfazl Namazi  3   4 , Ebrahim Faghihloo  5 , Abolfazl Akbari  4   6
Affiliations
Review

Role of the VEGF in virus-associated cancers

Shaian Tavakolian et al. Rev Med Virol. 2024 Jan.

Abstract

The role of numerous risk factors, including consumption of alcohol, smoking, having diet high in fat and sugar and many other items, on caner progression cannot be denied. Viral diseases are one these factors, and they can initiate some signalling pathways causing cancer. For example, they can be effective on providing oxygen and nutrients by inducing VEGF expression. In this review article, we summarised the mechanisms of angiogenesis and VEGF expression in cancerous tissues which are infected with oncoviruses (Epstein-Barr virus, Human papillomavirus infection, Human T-lymphotropic virus, Kaposi's sarcoma-associated herpesvirus, Hepatitis B and hepatitis C virus).

Keywords: EBV; HBV; HCV; HIV; HPV; HTLV; KSHV.

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