ASO Author Reflections: Complete Mesocolic Excision Versus Conventional Surgery for Right Colon Cancer (CoME-in trial): An Interim Analysis of a Multicenter, Randomized, Controlled Trial

M Degiuli^{1

2}, D Azzolina³, F Corcione⁴, U Bracale⁴, R Peltrini⁴, G Baldazzi⁵, G S Sica⁶, A Muratore⁷, E Jovine⁸, G Anania⁹, S Borin¹⁰, R Persiani¹¹, R Reddavid^{12

13}

Affiliations

¹ Department of Oncology, University of Turin, Torino, Italy.
² Department of Oncology, San Luigi Gonzaga University Hospital, Orbassano, Italy.
³ Department of Environmental and Preventive Sciences, University of Ferrara, Ferrara, Italy.
⁴ Department of General and Oncological Minimally Invasive Surgery, University of Naples Federico II, Naples, Italy.
⁵ ASST OVEST MILANESE, P.O. Nuovo Ospedale di Legnano, Legnano, Italy.
⁶ Minimally Invasive and Gastrointestinal Surgery Unit, Università e Policlinico Tor Vergata, Rome, Italy.
⁷ Edoardo Agnelli Hospital of Pinerolo, Pinerolo, Italy.
⁸ University of Bologna, IRCCS AOU of Bologna, Bologna, Italy.
⁹ Departement of Medical Science, Faculty of Medicine Pharmacy and Prevention, University of Ferrara, Ferrara, Italy.
¹⁰ Digestive Surgery European Institute of Oncology - IRCCS, Milan, Italy.
¹¹ General Surgery Unit, Fondazione Policlinico Universitario Agostino Gemelli, Catholic University, Rome, Italy.
¹² Department of Oncology, University of Turin, Torino, Italy. rossella.reddavid@unito.it.
¹³ Department of Oncology, San Luigi Gonzaga University Hospital, Orbassano, Italy. rossella.reddavid@unito.it.

Comment

M Degiuli et al. Ann Surg Oncol. 2024 Mar.

. 2024 Mar;31(3):1694-1695.

doi: 10.1245/s10434-023-14771-y. Epub 2023 Dec 12.

M Degiuli^{1

2}, D Azzolina³, F Corcione⁴, U Bracale⁴, R Peltrini⁴, G Baldazzi⁵, G S Sica⁶, A Muratore⁷, E Jovine⁸, G Anania⁹, S Borin¹⁰, R Persiani¹¹, R Reddavid^{12

13}

¹ Department of Oncology, University of Turin, Torino, Italy.
² Department of Oncology, San Luigi Gonzaga University Hospital, Orbassano, Italy.
³ Department of Environmental and Preventive Sciences, University of Ferrara, Ferrara, Italy.
⁴ Department of General and Oncological Minimally Invasive Surgery, University of Naples Federico II, Naples, Italy.
⁵ ASST OVEST MILANESE, P.O. Nuovo Ospedale di Legnano, Legnano, Italy.
⁶ Minimally Invasive and Gastrointestinal Surgery Unit, Università e Policlinico Tor Vergata, Rome, Italy.
⁷ Edoardo Agnelli Hospital of Pinerolo, Pinerolo, Italy.
⁸ University of Bologna, IRCCS AOU of Bologna, Bologna, Italy.
⁹ Departement of Medical Science, Faculty of Medicine Pharmacy and Prevention, University of Ferrara, Ferrara, Italy.
¹⁰ Digestive Surgery European Institute of Oncology - IRCCS, Milan, Italy.
¹¹ General Surgery Unit, Fondazione Policlinico Universitario Agostino Gemelli, Catholic University, Rome, Italy.
¹² Department of Oncology, University of Turin, Torino, Italy. rossella.reddavid@unito.it.
¹³ Department of Oncology, San Luigi Gonzaga University Hospital, Orbassano, Italy. rossella.reddavid@unito.it.

No abstract available

Comment on

A Randomized Phase III Trial of Complete Mesocolic Excision Compared with Conventional Surgery for Right Colon Cancer: Interim Analysis of a Nationwide Multicenter Study of the Italian Society of Surgical Oncology Colorectal Cancer Network (CoME-in trial).
Degiuli M, Aguilar AHR, Solej M, Azzolina D, Marchiori G, Corcione F, Bracale U, Peltrini R, Di Nuzzo MM, Baldazzi G, Cassini D, Sica GS, Pirozzi B, Muratore A, Calabrò M, Jovine E, Lombardi R, Anania G, Chiozza M, Petz W, Pizzini P, Persiani R, Biondi A, Reddavid R. Degiuli M, et al. Ann Surg Oncol. 2024 Mar;31(3):1671-1680. doi: 10.1245/s10434-023-14664-0. Epub 2023 Dec 12. Ann Surg Oncol. 2024. PMID: 38087139 Free PMC article. Clinical Trial.

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1. Di Buono G, Buscemi S, Cocorullo G, et al. Feasibility and safety of laparoscopic complete mesocolic excision (CME) for right-sided colon cancer: short-term outcomes. A randomized clinical study. Ann Surg. 2021;274(1):57–62. https://doi.org/10.1097/SLA.0000000000004557 . - DOI - PubMed
1. Degiuli M, Solej M, Resendiz Aguilar HA, Marchiori G, Reddavid R. Complete mesocolic excision in comparison with conventional surgery for right colon cancer: a nationwide multicenter study of the Italian society of surgical oncology colorectal cancer network (CoME-in trial). Study protocol for a randomized controlled trial. Jpn J Clin Oncol. 2022;52(10):1232–41. https://doi.org/10.1093/jjco/hyac116 . - DOI - PubMed
1. Degiuli M, Resendiz Aguilar HA, Solej M, et al. A randomized phase III trial of complete mesocolic excision in comparison with conventional surgery for right colon cancer. Interim analysis of a nationwide multicenter study of the Italian society of surgical oncology colorectal cancer network (CoME-in trial). Ann Surg Oncol. 2023. https://doi.org/10.1245/s10434-023-14664-0 . - DOI - PubMed