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Case Reports
. 2023 Dec 9;10(12):e01169.
doi: 10.14309/crj.0000000000001169. eCollection 2023 Dec.

Aseptic Liver Abscess in a Patient With Diversion Colitis

Mayan Eitan  1   2 , Fabiana Benjaminov  1   2 , Chen Zinger  1   2 , Yona Kitay Cohen  1   2 , Yehuda Ringel  1   2   3
Affiliations
Case Reports

Aseptic Liver Abscess in a Patient With Diversion Colitis

Mayan Eitan et al. ACG Case Rep J. .

Abstract

Aseptic abscess syndrome is a rare clinical entity mainly associated with systemic inflammatory conditions, particularly inflammatory bowel disease. The syndrome is characterized by an inflammatory infiltrate predominantly consisting of neutrophils, most commonly in the liver and spleen. We present a case of a patient with symptomatic diversion colitis diagnosed with a clinical and histological presentation consistent with aseptic abscess syndrome of the liver. Treatment and resolution of the inflamed colon was associated with complete disappearance of the liver lesions and normalization of liver enzymes. To the best of our knowledge, this is the first report suggesting the unique link between diversion colitis and aseptic liver abscess.

Keywords: diversion colitis; liver abnormalities; liver abscess.

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Figures

Figure 1.
Figure 1.
(A) PET FDG-CT pathological uptake of the rectum and mesorectal lymph nodes. (B) Abdominal CT showing 2 hypodense liver lesions, 0.8 cm in size, located in segment 7. (C) Abdominal MRI showing multiple lesions in both liver lobes, largest lesion size 2 cm, in the eighth segment. (D) First lesion biopsy showing mostly neutrophil infiltration and 2 giant cells consistent with severe acute inflammation. (E) Second lesion biopsy showing a bile duct infiltrated by neutrophils. CT, computed tomography; PET, positron emission tomography; MRI, magnetic resonance imaging.
See this image and copyright information in PMC

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