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Review
. 2023 Dec 13;15(726):eade9214.
doi: 10.1126/scitranslmed.ade9214. Epub 2023 Dec 13.

Data-driven science and diversity in the All of Us Research Program

Geoffrey S Ginsburg  1 , Joshua C Denny  1 , Sheri D Schully  1
Affiliations
Review

Data-driven science and diversity in the All of Us Research Program

Geoffrey S Ginsburg et al. Sci Transl Med. .

Abstract

The National Institutes of Health's All of Us Research Program is an accessible platform that hosts genomic and phenotypic data to be collected from 1 million participants in the United States. Its mission is to accelerate medical research and clinical breakthroughs with a special emphasis on diversity.

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Figures

Figure 1.
Figure 1.. Data and tools hosted on the All of Us Researcher Workbench.
The All of Us Researcher Workbench integrates five major sources of data collected from participants. The five data streams include survey data provided by participants, whole genome sequence data from participant DNA samples, physical measures collected directly from participants or electronic health records (EHR), and wearable data primarily from Fitbits ( https://www.researchallofus.org/data-tools/data-sources/). Shown are the number of participants from which curated data are available as of November 2023. The Researcher Workbench is a cloud-based platform that allows tiered access to these data types by researchers and the public through the All of Us Research Hub (https://www.researchallofus.org/). Each data type has tools to facilitate use in research. The public has access to summary data through the public browser, and researchers have access to more granular data in the registered tier and controlled tier. CREDIT: A. FISHER/SCIENCE TRANSLATIONAL MEDICINE
See this image and copyright information in PMC

References

    1. Precision Medicine Initiative Working Group, The Precision Medicine Initiative Cohort Program – Building a Research Foundation for 21st Century Medicine: Precision Medicine Initiative Working Group Report to the Advisory Committee to the Director, NIH https://www.nih.gov/sites/default/files/research-training/initiatives/pm... (2015).
    1. Mapes BM, Foster CS, Kusnoor SV et al. , Diversity and inclusion for the All of Us Research Program: A scoping review. PLoS ONE (2020) 15(7): e0234962. 10.1371/journal.pone.0234962 - DOI - PMC - PubMed
    1. https://allofus.nih.gov/funding-and-program-partners/health-care-provide... (accessed Nov 17, 2023)
    1. https://www.rand.org/pubs/research_reports/RR2578.html (accessed Nov 17, 2023)
    1. Fair A, Watson KS, Cohn EG et al. , Innovation in Large-Scale Research Programs: Elevating Research Participants to Governance Roles Through the All of Us Research Program Engagement Core. Acad Med (2022) 97:1794–1798. - PMC - PubMed

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