Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comment
. 2023 Dec 13;43(50):8579-8581.
doi: 10.1523/JNEUROSCI.1601-23.2023.

Evidence for a Primary Prior Deficit as a Mechanism of Auditory Hallucinations

Julia Rodriguez-Sanchez  1 , Hope Oloye  2 , Ingrid M Martin  3 , Daniel J Hauke  2
Affiliations
Comment

Evidence for a Primary Prior Deficit as a Mechanism of Auditory Hallucinations

Julia Rodriguez-Sanchez et al. J Neurosci. .
No abstract available

PubMed Disclaimer

Figures

Figure 1.
Figure 1.
Deficits in Bayesian inference hypothesized to underlie hallucinations. A, In Bayesian models (top), perceptions (posteriors) arise from the integration of sensory evidence (likelihood) with a priori expectations (prior) prescribed by Bayes theorem (bottom). B, An overreliance on prior expectations can arise from a primary prior deficit (Hypothesis 1), a primary sensory deficit (Hypothesis 2), or a primary sensory deficit leading to a secondary prior deficit (Hypothesis 3). The findings from Duhamel et al. (2023) favor Hypothesis 1.
See this image and copyright information in PMC

Comment on

References

    1. Benrimoh D, Fisher VL, Seabury R, Sibarium E, Mourgues C, Chen D, Powers A (2023) Evidence for reduced sensory precision and increased reliance on priors in hallucination-prone individuals in a general population sample. arXiv 2306.13832. - PMC - PubMed
    1. Cassidy CM, Balsam PD, Weinstein JJ, Rosengard RJ, Slifstein M, Daw ND, Abi-Dargham A, Horga G (2018) A perceptual inference mechanism for hallucinations linked to striatal dopamine. Curr Biol 28:503–514.e4. 10.1016/j.cub.2017.12.059 - DOI - PMC - PubMed
    1. Corlett PR, Horga G, Fletcher PC, Alderson-Day B, Schmack K, Powers AR (2019) Hallucinations and strong priors. Trends Cogn Sci 23:114–127. 10.1016/j.tics.2018.12.001 - DOI - PMC - PubMed
    1. Duhamel E, Mihali A, Horga G (2023) Effects of hallucination proneness and sensory resolution on prior biases in human perceptual inference of time intervals. J Neurosci 43:5365–5377. 10.1523/JNEUROSCI.0692-22.2023 - DOI - PMC - PubMed
    1. Hauke DJ, Charlton CE, Schmidt A, Griffiths J, Woods SW, Ford JM, Srihari VH, Roth V, Diaconescu AO, Mathalon DH (2023) Aberrant hierarchical prediction errors are associated with transition to psychosis: a computational single-trial analysis of the mismatch negativity. Biol Psychiatry Cogn Neurosci Neuroimaging. Advance online publication. Retrieved Aug 1, 2023. 10.1016/j.bpsc.2023.07.011. 10.1016/j.bpsc.2023.07.011 - DOI - DOI - PubMed

Publication types