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. 2023 Nov 29:5:1281529.
doi: 10.3389/fdgth.2023.1281529. eCollection 2023.

Evaluating passive physiological data collection during Spravato treatment

Todd M Solomon  1 , Matus Hajduk  1 , Martin Majernik  1 , Jamileh Jemison  1 , Alexander Deschamps  1 , Jenna Scoggins  1 , Adam Kolar  1 , Miguel Amável Pinheiro  1 , Peter Dubec  1 , Ondrej Skala  1 , Owen Muir  2 , Amanda Tinkelman  2 , Daniel R Karlin  1   3 , Robert Barrow  1
Affiliations

Evaluating passive physiological data collection during Spravato treatment

Todd M Solomon et al. Front Digit Health. .

Abstract

Spravato and other drugs with consciousness-altering effects show significant promise for treating various mental health disorders. However, the effects of these treatments necessitate a substantial degree of patient monitoring which can be burdensome to healthcare providers and may make these treatments less accessible for prospective patients. Continuous passive monitoring via digital devices may be useful in reducing this burden. This proof-of-concept study tested the MindMed Session Monitoring System™ (MSMS™), a continuous passive monitoring system intended for use during treatment sessions involving pharmaceutical products with consciousness-altering effects. Participants completed 129 Spravato sessions with MSMS at an outpatient psychiatry clinic specializing in Spravato treatment. Results indicated high rates of data quality and self-reported usability among participants and health care providers (HCPs). These findings demonstrate the potential for systems such as MSMS to be used in consciousness-altering treatment sessions to assist with patient monitoring.

Keywords: depression; dissociative; esketamine; hallucinogen; mental health; passive monitoring; psychedelic; spravato.

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Conflict of interest statement

TS, JJ, MH, MM, AD, PD, AK, MP, OS, DK and RB are employed by Mind Medicine, Inc., the Sponsor of this research. OM and AT were employed by Brooklyn Minds Psychiatry, the research site, during this study. All funding for this research was provided by the study sponsor, Mind Medicine, Inc.

Figures

Figure 1
Figure 1
Study design and activities, including screening, per each participant visit.
Figure 2
Figure 2
Number of Spravato sessions with or without MSMS data collection completed by each participant over the course of the study.
Figure 3
Figure 3
Mean data coverage (%) per participant with a colored heatmap.
See this image and copyright information in PMC

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