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Case Reports
. 2023 Nov 13;15(11):e48757.
doi: 10.7759/cureus.48757. eCollection 2023 Nov.

Sinonasal and Skull Base Metastatic Renal Cell Carcinoma: A Case Series

Andrew O Hess  1 , Russell S Terry  2 , Brian C Lobo  3 , Jeb M Justice  3
Affiliations
Case Reports

Sinonasal and Skull Base Metastatic Renal Cell Carcinoma: A Case Series

Andrew O Hess et al. Cureus. .

Abstract

Metastatic lesions to the paranasal sinuses and skull base, while rare, carry a poor prognosis. Renal cell carcinoma has been reported in multiple case reports to be one of the most common distant malignancies to spread to the paranasal sinuses; however, it is often unrecognized by physicians, and thus treatment is delayed. To increase awareness of this disease process, we describe three cases of metastatic renal cell carcinoma to the sinonasal cavity, which is the largest case series in the literature to date.

Keywords: clear cell renal carcinoma; renal cell carcinoma (rcc); renal cell carcinoma metastasis; sinonasal metastasis; skull base tumors.

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Conflict of interest statement

The authors have declared financial relationships, which are detailed in the next section.

Figures

Figure 1
Figure 1. Image depicting RCC metastasis to the IT fossa, middle fossa, and sphenoid sinus (*) as seen on coronal CT of the head (A); image of RCC metastasis to the IT fossa, middle fossa, and sphenoid sinus (*) as seen on coronal MRI of the head (B).
RCC: Renal cell carcinoma.
Figure 2
Figure 2. Image depicting RCC metastasis to the sphenoid, posterior ethmoids, sella, and clivus (*) as seen on coronal CT of head (A), image of RCC metastasis to the sphenoid, posterior ethmoids, sella, and clivus (*) as seen on axial MRI of head (B).
RCC: Renal cell carcinoma.
Figure 3
Figure 3. Image depicting sinus mass (*) as seen on coronal CT of head (A), image of sinus mass (*) and brain mass (+) as seen on coronal MRI of head (B), sinus mass (*) as seen on axial MRI of head (C).
See this image and copyright information in PMC

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