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. 2024 Jan;17(1):e012426.
doi: 10.1161/CIRCEP.123.012426. Epub 2023 Dec 14.

Efficacy of Intravenous Nitrates for the Prevention of Coronary Artery Spasm During Pulsed Field Ablation of the Mitral Isthmus

Roberto Menè  1   2 , Serge Boveda  1 , Domenico Giovanni Della Rocca  3 , Vasileios Sousonis  1 , Giampaolo Vetta  3 , Sarah Zeriouh  1 , Ioannis Doundoulakis  3 , Andres Betancur  1   3 , Mohamed Benadel  1 , Nicolas Combes  1 , Andrea Sarkozy  3 , Gian Battista Chierchia  3 , Carlo de Asmundis  3 , Jean Paul Albenque  1 , Stéphane Combes  1
Affiliations

Efficacy of Intravenous Nitrates for the Prevention of Coronary Artery Spasm During Pulsed Field Ablation of the Mitral Isthmus

Roberto Menè et al. Circ Arrhythm Electrophysiol. 2024 Jan.
No abstract available

Keywords: atrial fibrillation; catheter ablation; coronary vasospasm; electroporation; isosorbide dinitrate; nitrates.

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Conflict of interest statement

Disclosures Dr Boveda consults for Medtronic, Boston Scientific, MicroPort, and ZOLL. Dr Sarkozy is a consultant for Biosense Webster, Medtronic, Biotronik, and MicroPort. Dr Battista Chierchia received compensation for teaching purposes and proctoring from Medtronic, Abbott, Biotronik, Boston Scientific, and Acutus Medical. Dr de Asmundis receives research grants on behalf of the center from Biotronik, Medtronic, Abbott, LivaNova, Boston Scientific, AtriCure, Philips, and Acutus Medical and compensation for teaching purposes and proctoring from Medtronic, Abbott, Biotronik, LivaNova, Boston Scientific, AtriCure, Acutus Medical, and Daiichi Sankyo. Dr Albenque consults for Abbott and Volta Medical. The other authors report no conflicts.

Figures

Figure.
Figure.
Coronary artery spasm occurring during pulsed field ablation of the mitral isthmus. A, Real-time integration of fluoroscopy with a computed tomography reconstruction of the left atrium (blue) and the left circumflex coronary artery (orange) in the left anterior oblique view showing the position of the Farawave catheter during the applications on the mitral isthmus. B, Coronary angiography demonstrating a spasm of the mid-left circumflex coronary artery (red arrow) following pulsed field ablation of the mitral isthmus. C, ECG during the coronary spasm event showing ST-segment elevation in the inferior and lateral leads. D, Coronary angiography showing spasm resolution following intracoronary administration of nitrates. E, ECG demonstrating complete regression of the ischemic signs following spasm resolution.
See this image and copyright information in PMC

References

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