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. 1986 Dec;7(4):323-6.
doi: 10.1016/s0167-8140(86)80061-5.

Alpha/beta value and the importance of size of dose per fraction for late complications in the supraglottic larynx

B Maciejewski, J M Taylor, H R Withers

Alpha/beta value and the importance of size of dose per fraction for late complications in the supraglottic larynx

B Maciejewski et al. Radiother Oncol. 1986 Dec.

Abstract

In a group of 155 cases with squamous cell carcinoma of the supraglottic larynx (T3-4N0M0), with 3-year local control after radiotherapy, 21 late complications were noted. Using two different methods, an alpha/beta value of 3.8 Gy was calculated. A strong correlation between the risk of late effect in the larynx and size of dose per fraction was found; there was no influence of overall treatment time.

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