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Review
. 2023 Jan-Dec:11:23247096231217823.
doi: 10.1177/23247096231217823.

Actinomycotic Sinomaxillary Infection in a COVID-19 Patient: A Case Report and Review of the Literature

Affiliations
Review

Actinomycotic Sinomaxillary Infection in a COVID-19 Patient: A Case Report and Review of the Literature

Amirhossein Moaddabi et al. J Investig Med High Impact Case Rep. 2023 Jan-Dec.

Abstract

Individuals with COVID-19 are prone to a variety of infections due to immune dysregulation. The present report presents a case of actinomycotic infection in the maxillary bone and sinus region in a patient with a history of COVID-19. This case report highlights the importance of considering bacterial infections including actinomycosis when encountering destructive lesions resembling more prevalent fungal infections due to different therapeutic medication protocols. In addition, a literature review of the existing reports of similar post-COVID-19 actinomycotic infection is presented.

Keywords: COVID-19; actinomycete; actinomycosis.

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Conflict of interest statement

Declaration of Conflicting InterestsThe author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.

Figures

Figure 1.
Figure 1.
Intraoral photograph depicting exposed roots of the right maxillary first molar with surrounding inflammation.
Figure 2.
Figure 2.
Cone-beam computed tomographic images in (A) coronal and (B) axial sections depicting the lytic and destructive lesion on the right side of the maxilla.
Figure 3.
Figure 3.
Histopathological hematoxylin and eosin staining of the sample indicating focus of actinomycosis with surrounding inflammatory response.
Figure 4.
Figure 4.
Intraoral photograph depicting resolution of inflammation and favorable healing of the infection.

References

    1. Weiss SR, Leibowitz JL. Coronavirus pathogenesis. Adv Virus Res. 2011;81:85-164. - PMC - PubMed
    1. Ng WH, Tipih T, Makoah NA, et al.. Comorbidities in SARS-CoV-2 patients: a systematic review and meta-analysis. mbio. 2021;12:e03647-20. - PMC - PubMed
    1. Wolff D, Nee S, Hickey NS, Marschollek M. Risk factors for Covid-19 severity and fatality: a structured literature review. Infection. 2021;49(1):15-28. - PMC - PubMed
    1. Chen G, Wu D, Guo W, et al.. Clinical and immunological features in severe and moderate forms of coronavirus disease. J Clin Invest. 2019;82:137244. - PMC - PubMed
    1. Yang J, Zheng Y, Gou X, et al.. Prevalence of comorbidities and its effects in patients infected with SARS-CoV-2: a systematic review and meta-analysis. Int J Infect Dis. 2020;94: 91-95. - PMC - PubMed

MeSH terms