Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2023 Dec 15;23(1):122.
doi: 10.1186/s40644-023-00646-8.

Comparing endoscopic ultrasonography and double contrast-enhanced ultrasonography in the preoperative diagnosis of gastric stromal tumor

Huiliao He #  1 , Tingting Tang #  1 , Xiaohua Wang  1 , Lingling Zhou  2 , Liang Wang  3
Affiliations

Comparing endoscopic ultrasonography and double contrast-enhanced ultrasonography in the preoperative diagnosis of gastric stromal tumor

Huiliao He et al. Cancer Imaging. .

Abstract

Background: This study was designed to perform a comparative analysis between endoscopic ultrasonography (EUS) and double contrast-enhanced ultrasonography (DCEUS) for the preoperative diagnosis of gastric stromal tumors (GSTs).

Methods: A retrospective study was conducted involving 139 patients with histologically confirmed GSTs. All patients preoperatively underwent DCEUS and EUS. The pathology reports were treated as the baseline and were retrospectively compared with the findings of EUS and DCEUS.

Results: Of the 139 lesions, 120 and 113 were correctly identified by DCEUS and EUS, respectively, with an accuracy of 86.3% and 81.3%. The results revealed an insignificant difference between these two methods (p = 0.189).

Conclusions: DCEUS can display not only the locations, sizes, shapes, borders, internal echoes, but also show the blood perfusion patterns of GSTs. It is a highly accurate, noninvasive, and convenient method to be used at the pre-treatment stage.

Keywords: Diagnosis; Endoscopic Ultrasonography; Gastrointestinal stromal tumors; Ultrasonography.

PubMed Disclaimer

Conflict of interest statement

The authors declare that they have no competing interests.

Figures

Fig. 1
Fig. 1
A 53-year-old man with a gastric stromal tumor (GST). (A, B) Endoscopic ultrasonography (EUS) detected a solid, round, and hypoechoic tumor(calipers) in the gastric antrum. (C) Single oral contrast-enhanced ultrasonography (SOCEUS) showed a round, hypoechoic, and heterogeneous mass (calipers) located in the antrum of the stomach
Fig. 2
Fig. 2
A 49-year-old woman with a GST. (A) SOCEUS exhibited a round, hypoechoic, and homogeneous tumor (calipers) in the gastric body. (B) DCEUS showed a peripheral ring-like hyperenhancement sign on the tumor (arrows)
Fig. 3
Fig. 3
A 46-year-old woman with a GST. (A) SOCEUS exhibited an oval-shaped and homogeneous hypoechoic tumor (calipers) in the gastric body. (B) DCEUS showed the tumor demonstrated homogeneous enhancement
Fig. 4
Fig. 4
A 60-year-old woman with a GST. (A) SOCEUS exhibited a large, ovoid, hypoechoic, and heterogeneous tumor (calipers) in the gastric fundus, cyst formation could be detected in the mass. (B) DCEUS showed that the tumor demonstrated heterogeneous enhancement
See this image and copyright information in PMC

Similar articles

See all similar articles

Cited by

References

    1. de Pinieux G, Karanian M, Le Loarer F, Le Guellec S, Chabaud S, Terrier P, et al. Nationwide incidence of sarcomas and connective tissue tumors of intermediate malignancy over four years using an expert pathology review network. PLoS ONE. 2021;16:e0246958. doi: 10.1371/journal.pone.0246958. - DOI - PMC - PubMed
    1. Yamamoto H, Oda Y. Gastrointestinal stromal Tumor: recent advances in pathology and genetics. Pathol Int. 2015;65:9–18. doi: 10.1111/pin.12230. - DOI - PubMed
    1. Ren C, Wang S, Zhang S. Development and validation of a nomogram based on CT images and 3D texture analysis for preoperative prediction of the malignant potential in gastrointestinal stromal tumors. Cancer Imaging. 2020;20(1):5. doi: 10.1186/s40644-019-0284-7. - DOI - PMC - PubMed
    1. Jiaxin L, Peiyun Z, Zheng T, Wei Y, Shanshan S, Lei R, et al. Comparison of prognostic prediction models for rectal gastrointestinal stromal Tumor. Aging. 2020;12:11416–30. doi: 10.18632/aging.103204. - DOI - PMC - PubMed
    1. Meng FS, Zhang ZH, Hong YY, Li DJ, Lin JQ, Chen X, et al. Comparison of endoscopic submucosal dissection and Surgery for the treatment of gastric submucosal tumors originating from the muscularis propria layer: a single-center study (with video) Surg Endosc. 2016;30:5099–107. doi: 10.1007/s00464-016-4860-7. - DOI - PubMed