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. 2024 Apr;46(2):390-394.
doi: 10.1111/ijlh.14208. Epub 2023 Dec 17.

Use of the oxygen gradient ektacytometry in the dose titration of hydroxyurea therapy in children with sickle cell disease

Maite E Houwing  1 , Jennifer Bos  2 , Richard van Wijk  2 , Eduard J van Beers  3 , Marjon H Cnossen  1 , Minke A E Rab  2   4 ; SCORE consortium
Collaborators, Affiliations

Use of the oxygen gradient ektacytometry in the dose titration of hydroxyurea therapy in children with sickle cell disease

Maite E Houwing et al. Int J Lab Hematol. 2024 Apr.
No abstract available

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References

REFERENCES

    1. Piel FB, Patil AP, Howes RE, et al. Global epidemiology of sickle haemoglobin in neonates: a contemporary geostatistical model-based map and population estimates. Lancet. 2013;381(9861):142-151. doi:10.1016/S0140-6736(12)61229-X
    1. Hoppe C, Vichinsky E, Quirolo K, Van Warmerdam J, Allen K, Styles L. Use of hydroxyurea in children ages 2 to 5 years with sickle cell disease. J Pediatr Hematol Oncol. 2000;22(4):330-334. https://journals.lww.com/jpho-online/Fulltext/2000/07000/Use_of_Hydroxyu...
    1. Yawn BP, Buchanan GR, Afenyi-Annan AN, et al. Management of sickle cell disease: summary of the 2014 evidence-based report by expert panel members. Jama. 2014;312(10):1033-1048. doi:10.1001/jama.2014.10517
    1. Rab MAE, van Oirschot BA, Bos J, et al. Rapid and reproducible characterization of sickling during automated deoxygenation in sickle cell disease patients. Am J Hematol. 2019;94(February):575-584. doi:10.1002/ajh.25443
    1. Rab MAE, Kanne CK, Bos J, et al. Oxygen gradient ektacytometry derived-biomarkers are associated with vaso-occlusive crises and correlate with treatment response in sickle cell disease. Am J Hematol. 2021;96(1):E29-E32. doi:10.1002/ajh.26031

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