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Review
. 2023 Dec 18;185(51):V06230371.

The role of immunotherapy in the treatment of colorectal cancer

[Article in Danish]
Adile Orhan  1   2 , Sara Mørup  1 , Laurids Østergaard Poulsen  3 , Per Pfeiffer  4 , Camilla Qvortrup  5 , Ismail Gögenur  1
Affiliations
  • PMID: 38105736
Free article
Review

The role of immunotherapy in the treatment of colorectal cancer

[Article in Danish]
Adile Orhan et al. Ugeskr Laeger. .
Free article

Abstract

In Denmark, around 4,500 people are diagnosed with colorectal cancer (CRC) annually. This review investigates that while the efficacy of immunotherapy in CRC is still being studied, immunotherapy is currently only indicated in the treatment of mismatch-repair deficient (dMMR) metastatic CRC, which accounts for 10-15% of patients. Recent studies indicate high rates of pathologic response in dMMR CRC treated with pre-operative immunotherapy while large-scale studies on novel immunotherapy combinations are ongoing.

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