The relative importance of N-oxidation and N-demethylation in the metabolism of trimethylamine in man
- PMID: 3810655
- DOI: 10.1016/0300-483x(87)90001-1
The relative importance of N-oxidation and N-demethylation in the metabolism of trimethylamine in man
Abstract
The metabolism of orally administered trimethylamine has been studied in 4 male volunteers at 2 dose levels. N-Oxidation was the major route of metabolism whilst N-demethylation was negligible and only significant at the higher dose level.
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