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. 1987 Feb;43(2):117-21.
doi: 10.1016/0300-483x(87)90001-1.

The relative importance of N-oxidation and N-demethylation in the metabolism of trimethylamine in man

The relative importance of N-oxidation and N-demethylation in the metabolism of trimethylamine in man

M Al-Waiz et al. Toxicology. 1987 Feb.

Abstract

The metabolism of orally administered trimethylamine has been studied in 4 male volunteers at 2 dose levels. N-Oxidation was the major route of metabolism whilst N-demethylation was negligible and only significant at the higher dose level.

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