Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2023 Nov 15;15(11):e48858.
doi: 10.7759/cureus.48858. eCollection 2023 Nov.

Aortoiliac Occlusion in a Rare Instance of Leriche Syndrome Type I in a 65-Year-Old Woman With Chronic Leg Discomfort Refractory to Pregabalin

Affiliations
Case Reports

Aortoiliac Occlusion in a Rare Instance of Leriche Syndrome Type I in a 65-Year-Old Woman With Chronic Leg Discomfort Refractory to Pregabalin

Shreya Rani et al. Cureus. .

Abstract

Aortoiliac occlusive disease (AIOD), also known as Leriche syndrome, is a form of peripheral artery disease (PAD) that involves narrowing, and in severe cases, complete occlusion, of infrarenal abdominal aorta and/or iliac and femoropopliteal arteries. It classically presents as a triad of symptoms, i.e., leg pain, erectile dysfunction, and abnormally weak or absent femoral pulses. If untreated, it can progress to ischemia and gangrene of the affected regions of pelvis and lower extremities. Like any other PAD, AIOD is most commonly caused by atherosclerosis and usually occurs in strong association with severe cardiovascular diseases. Due to the rarity of this disease, its incidence and prevalence are still unknown making it harder to diagnose especially in patients without the classic risk factors and typical presentation. We report a case of AIOD in a 65-year-old woman who presented with atypical symptoms. She was diagnosed with AIOD type I upon further investigation, which was managed successfully.

Keywords: aorto-occlusive disease; atherosclerosis; cardio vascular disease; leriche syndrome; peripheral arterial diseases.

PubMed Disclaimer

Conflict of interest statement

The authors have declared that no competing interests exist.

Figures

Figure 1
Figure 1. Peripheral angiography, arrow pointing at obstruction at the level of aortic bifurcation with no blood flow to the right iliofemoral arteries and diminished blood flow to the left iliofemoral arteries.
Figure 2
Figure 2. CTA, arrow pointing at diminished blood flow to the iliofemoral arteries
CTA: Computed tomography angiography

Similar articles

Cited by

References

    1. Pathophysiology of atherothrombosis: mechanisms of thrombus formation on disrupted atherosclerotic plaques. Asada Y, Yamashita A, Sato Y, Hatakeyama K. Pathol Int. 2020;70:309–322. - PMC - PubMed
    1. Epidemiology of peripheral artery disease: narrative review. Horváth L, Németh N, Fehér G, Kívés Z, Endrei D, Boncz I. Life (Basel) 2022;12 - PMC - PubMed
    1. Anatomical significance in aortoiliac occlusive disease. Wooten C, Hayat M, du Plessis M, et al. Clin Anat. 2014;27:1264–1274. - PubMed
    1. Valentine EA, Andrew Ochroch E. Essentials of Cardiac Anesthesia for Noncardiac Surgery. Elsevier; 2019. Vascular surgery: endovascular and open surgery; pp. 313–339.
    1. Minimally invasive management of severe aortoiliac occlusive disease. Pascarella L, Aboul Hosn M. J Laparoendosc Adv Surg Tech A. 2018;28:562–568. - PubMed

Publication types

LinkOut - more resources