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Review
. 2023 Oct 18:6:100111.
doi: 10.1016/j.crphys.2023.100111. eCollection 2023.

Advances in vaginal bioengineering: Applications, techniques, and needs

Lily M Buchanan  1 , Mari J E Domingo  2 , Shelby E White  2 , Triniti N Vanoven  1   3 , Niyousha Karbasion  4 , Matthew R Bersi  4 , Isaac J Pence  1   3   5   6 , Maria Florian-Rodriguez  7   8 , Kristin S Miller  1   3   7   9
Affiliations
Review

Advances in vaginal bioengineering: Applications, techniques, and needs

Lily M Buchanan et al. Curr Res Physiol. .
No abstract available

PubMed Disclaimer

Conflict of interest statement

The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

Figures

Fig. 1
Fig. 1
This diagram shows the layers and microstructural components of the vagina. The composition and organization of these components (smooth muscle cells, elastic fibers, and collagen fibers) determine the mechanical behavior of the organ. Some figure components created in Biorender.com.
Fig. 2
Fig. 2
This chart is a visual overview of the various functions and roles the vagina plays throughout life, as well as the clinical diseases and conditions that drive the need for innovation through bioengineering approaches. Some figure components created using Biorender.com.
Fig. 3
Fig. 3
This table provides at-a-glance references for the intersection of models (rodent, rabbit, sheep, NHP, human) and bioengineering approaches (2-D culture, 3-D culture, MPS, biomaterials, biomechanics, imaging, and computational models. This is not an exhaustive table-additional discussion of recent work can be found in the respective sections. Figure created using Biorender.com.
Fig. 4
Fig. 4
This visual representation of literature is intended to highlight unmet needs and opportunities for investigation of vaginal (patho)physiology using imaging approaches. Part (a.) displays a radar chart of the discussed vaginal conditions and the respective imaging modalities for each. The solid lines indicate clinically applied technologies, while the dashed lines represent investigational techniques. The radii are representative of the reviewed literature and relevant citations. Part (b.) exhibits a Venn diagram relating to the results of the aforementioned imaging types.
See this image and copyright information in PMC

References

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