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Review
. 2023 Dec 12;57(Suppl 1):209-217.
doi: 10.1007/s43465-023-01049-4. eCollection 2023 Dec.

Diabetes and Osteoporosis

Trupti Nagendra Prasad  1 , Durairaj Arjunan  1 , Rimesh Pal  1 , Sanjay Kumar Bhadada  1
Affiliations
Review

Diabetes and Osteoporosis

Trupti Nagendra Prasad et al. Indian J Orthop. .

Abstract

Bone fragility is an emerging complication of diabetes. People with diabetes are at a significantly higher risk of fractures compared to the general population. Bone fragility occurs in diabetes as a result of complex and poorly understood mechanisms occurring at the cellular level contributed by vascular, inflammatory and mechanical derangements. Bone mineral density (BMD) as assessed by DEXA is low in type 1 diabetes. Type 2 diabetes has a high risk of fracture despite a normal to raised BMD. DEXA thus underestimates the fracture risk in diabetes. Data are scare regarding the efficacy of the available therapies in this low bone turnover state.

Keywords: Bone fragility; Bone mineral density; Diabetes mellitus; Osteoporosis.

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Conflict of interest statement

Conflict of InterestThe authors declare that they have no conflict of interest.

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