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. 2023 Dec 12:18:2971-2983.
doi: 10.2147/COPD.S436879. eCollection 2023.

Global, Regional, and National Burden of COPD Attributable to Occupational Particulate Matter, Gases, and Fumes, 1990-2019: Findings from the Global Burden of Disease Study 2019

Xin Su #  1 , Hengqiong Gu #  1 , Fajun Li  2 , Donglei Shi  3 , Zhaojun Wang  3
Affiliations

Global, Regional, and National Burden of COPD Attributable to Occupational Particulate Matter, Gases, and Fumes, 1990-2019: Findings from the Global Burden of Disease Study 2019

Xin Su et al. Int J Chron Obstruct Pulmon Dis. .

Abstract

Background: A study aimed to estimate the burden of Chronic obstructive pulmonary disease (COPD) caused by occupational exposure to particulate matter, gases, and fumes in 204 countries from 1990 to 2019.

Methods: Data on the deaths number, age-standardized mortality rates (ASMR), and age-standardized disability-adjusted life years (DALYs) rates (ASDR) of COPD attributable to occupational particulate matter, gases, and fumes were collected from the GBD study 2019. We also investigated the association between the ASDR and SDI.

Results: There were 517.7 thousand deaths [95% UI: 413.9 to 634.5] in 2019. The number of deaths increased from 1990 to 2019. The ASMR and ASDR were 6.61 (5.24 to 8.17) and 143.02 (118.56 to 168.69) in 2019, respectively, representing a 46% and 44.5% decrease since 1990. China had the highest number of deaths [200,748.4 (151,897.6 to 260,703.9)], while Nepal had the highest ASMR [39 (27.7 to 50)] and ASDR [724.5 (549 to 894.2)]. Males and females 75-79 and 80-84 years old had the highest number of COPD deaths. A negative correlation was observed when SDI > 0.4, whereas a positive correlation was found when SDI < 0.4.

Conclusion: From 1990 to 2019, there was an increase in the number of deaths, but a decline in ASMR and ASDR globally. Besides, there was a heterogeneous burden of COPD attributable to occupational particulate matter, gases, and fumes across regions and countries. It is important to develop and implement strategies to prevent and reduce the burden of COPD attributable to occupational particulate matter, gases, and fumes.

Keywords: age-standardized rates; chronic obstructive pulmonary disease; deaths number; fumes; gases; global burden of disease; occupational particulate matter.

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Conflict of interest statement

The authors declare no conflicts of interest in this work.

Figures

Figure 1
Figure 1
The deaths number (A), DALYs number (B), ASMR per 100,000 population (C), ASDR per 100,000 population (D) of chronic obstructive pulmonary disease attributable to occupational particulate matter, gases, and fumes by sex, 1990–2019.
Figure 2
Figure 2
Global distribution of chronic obstructive pulmonary disease attributable to occupational particulate matter, gases, and fumes burden in terms of deaths (A), ASMR (B) and ASDR (C) in 2019.
Figure 3
Figure 3
Global number of deaths and death rate (A) and global number of DALYs and DALY rate per 100,000 population (B) of chronic obstructive pulmonary disease attributable to occupational particulate matter, gases, and fumes by age and sex in 2019. DALY, disability-adjusted life years.
Figure 4
Figure 4
Age-standardised DALY rates (ASDR) of chronic obstructive pulmonary disease attributable to occupational particulate matter, gases, and fumes for 21 GBD regions by Socio-demographic Index, 1990–2019. Expected values based on Socio-demographic Index and disease rates in all locations are shown as the black line.
See this image and copyright information in PMC

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