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Case Reports
. 2024 Apr;52(2):691-696.
doi: 10.1007/s15010-023-02151-3. Epub 2023 Dec 19.

Postpartum cryptococcosis in an HIV-negative patient

Malin Gottschling  1 , Stefan Blaas  2 , Florian Geismann  2 , Christoph Lerzer  2 , Maximilian Malfertheiner  2 , Bernd Salzberger  3 , Florian Hitzenbichler  3 , Stefanie Scharf  4 , Florian Weber  5 , Arno Mohr  2
Affiliations
Case Reports

Postpartum cryptococcosis in an HIV-negative patient

Malin Gottschling et al. Infection. 2024 Apr.

Abstract

Purpose and methods: We present an unusual case of an HIV-negative patient with postpartum pulmonary cryptococcosis and cryptococcemia.

Results: The diagnostic methods and treatment of cryptococcosis in a postpartum patient are presented in this case report. Due to anaphylaxis to liposomal amphotericin B, desensitisation to the drug was performed.

Conclusion: We would like to raise awareness about rare infections such as cryptococcosis in pregnancy and the postpartum period. In addition, we were able to document a successful desensitisation to liposomal amphotericin B.

Keywords: Cryptococcemia; Cryptococcosis; Desensitisation; Liposomal amphotericin B; Postpartum infection.

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References

    1. Cameron ML, Bartlett JA, Gallis HA, Waskin HA. Manifestations of pulmonary cryptococcosis in patients with acquired immunodeficiency syndrome. Rev Infect Dis. 1991;13:64–7. https://doi.org/10.1093/clinids/13.1.64 . - DOI - PubMed
    1. Pappas PG, Perfect JR, Cloud GA, Larsen RA, Pankey GA, Lancaster DJ, Henderson H, Kauffman CA, Haas DW, Saccente M, Hamill RJ, Holloway MS, Warren RM, Dismukes WE. Cryptococcosis in human immunodeficiency virus-negative patients in the era of effective azole therapy. Clin Infect Dis. 2001;33:690–9. https://doi.org/10.1086/322597 . - DOI - PubMed
    1. Emmons CW. Saprophytic sources of Cryptococcus neoformans associated with the pigeon (Columba livia). Am J Hyg. 1955;62:227–32. https://doi.org/10.1093/oxfordjournals.aje.a119775 . - DOI - PubMed
    1. Velagapudi R, Hsueh YP, Geunes-Boyer S, Wright JR, Heitman J. Spores as infectious propagules of Cryptococcus neoformans. Infect Immun. 2009;77:4345–55. https://doi.org/10.1128/IAI.00542-09 . (Epub 2009 Jul 20). - DOI - PubMed - PMC
    1. Setianingrum F, Rautemaa-Richardson R, Denning DW. Pulmonary cryptococcosis: a review of pathobiology and clinical aspects. Med Mycol. 2019;57:133–50. https://doi.org/10.1093/mmy/myy086 . - DOI - PubMed

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