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Comment
. 2023 Dec 13;3(12):100456.
doi: 10.1016/j.xgen.2023.100456.

Mapping the genetic and phenotypic landscape of neonatal C3 and C4 protein concentrations

Leanna M Hernandez  1
Affiliations
Comment

Mapping the genetic and phenotypic landscape of neonatal C3 and C4 protein concentrations

Leanna M Hernandez. Cell Genom. .

Abstract

The complement system is crucial for innate immunity and has been linked to autoimmune and psychiatric disorders. Borbye-Lorenzen et al.1 perform GWASs and PheWASs of neonatal C3/C4 protein concentrations, finding multiple genome-wide significant loci, and identify sex-specific associations between C3 protein concentration and C4 copy number with risk for schizophrenia.

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Conflict of interest statement

The author declares no competing interests.

Comment on

References

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