Brain metastasis of a urothelial neuroendocrine carcinoma: A double pitfall for neuropathologists and DNA-methylation profiling

Arnault Tauziède-Espariat¹, Julien Masliah-Planchon², Suzanne Tran^{3

4}, Mathilde Filser², Raphaël Saffroy⁵, Dorian Bochaton¹, Lauren Hasty¹, Suhan Senova⁶, Paul Kauv⁷, Karima Mokhtari^{3

4}, Clovis Adam⁸, Nicolas Poté⁹, Fabrice Chrétien¹, Alice Métais^{1

10}, Pascale Varlet^{1

10}, Franck Bielle^{3

4}, Alice Laurenge¹¹

Affiliations

¹ Department of Neuropathology, GHU-Paris Psychiatrie et Neurosciences, Hôpital Sainte-Anne, Paris, France.
² Institut Curie, Laboratory of Somatic Genetics, PMDT, Paris Sciences Lettres Research University, Paris, France.
³ Sorbonne Université, AP-HP, Institut du Cerveau - Paris Brain Institute - ICM, Inserm, CNRS, Hôpitaux Universitaires La Pitié Salpêtrière - Charles Foix, Paris, France.
⁴ Department of Neuropathology, Hôpitaux Universitaires La Pitié Salpêtrière - Charles Foix, Paris, France.
⁵ Department of Biochemistry and Oncogenetics, Paul Brousse Hospital, Villejuif, France.
⁶ Department of Neurosurgery, Henri Mondor Hospital, Université Paris Est Créteil; Unité INSERM U955 IMRB, Neuropsychiatrie Translationnelle, Créteil, France.
⁷ Department of Radiology, Henri Mondor Hospital, Créteil, France.
⁸ Department of Pathology, Bicêtre Hospital, Le Kremlin-Bicêtre, France.
⁹ Department of Pathology, Beaujon Hospital, Clichy, France.
¹⁰ Université Paris Cité, Institute of Psychiatry and Neuroscience of Paris (IPNP), INSERM U1266, Ima-brain Team, Paris, France.
¹¹ Department of Neurology 2-Mazarin, Sorbonne Université, Inserm, CNRS, UMR S 1127, Institut du Cerveau Et de La Moelle Épinière, ICM, AP-HP, Hôpitaux Universitaires La Pitié Salpêtrière - Charles Foix, Paris, France.

Arnault Tauziède-Espariat et al. Neuropathol Appl Neurobiol. 2024 Feb.

. 2024 Feb;50(1):e12951.

doi: 10.1111/nan.12951.

¹ Department of Neuropathology, GHU-Paris Psychiatrie et Neurosciences, Hôpital Sainte-Anne, Paris, France.
² Institut Curie, Laboratory of Somatic Genetics, PMDT, Paris Sciences Lettres Research University, Paris, France.
³ Sorbonne Université, AP-HP, Institut du Cerveau - Paris Brain Institute - ICM, Inserm, CNRS, Hôpitaux Universitaires La Pitié Salpêtrière - Charles Foix, Paris, France.
⁴ Department of Neuropathology, Hôpitaux Universitaires La Pitié Salpêtrière - Charles Foix, Paris, France.
⁵ Department of Biochemistry and Oncogenetics, Paul Brousse Hospital, Villejuif, France.
⁶ Department of Neurosurgery, Henri Mondor Hospital, Université Paris Est Créteil; Unité INSERM U955 IMRB, Neuropsychiatrie Translationnelle, Créteil, France.
⁷ Department of Radiology, Henri Mondor Hospital, Créteil, France.
⁸ Department of Pathology, Bicêtre Hospital, Le Kremlin-Bicêtre, France.
⁹ Department of Pathology, Beaujon Hospital, Clichy, France.
¹⁰ Université Paris Cité, Institute of Psychiatry and Neuroscience of Paris (IPNP), INSERM U1266, Ima-brain Team, Paris, France.
¹¹ Department of Neurology 2-Mazarin, Sorbonne Université, Inserm, CNRS, UMR S 1127, Institut du Cerveau Et de La Moelle Épinière, ICM, AP-HP, Hôpitaux Universitaires La Pitié Salpêtrière - Charles Foix, Paris, France.

No abstract available

Keywords: DNA-methylation; OLIG2; medulloblastoma; neuroendocrine; urothelial carcinoma.

References

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