Effects of a medication adherence app among medically underserved adults with chronic illness: a randomized controlled trial
- PMID: 38127174
- PMCID: PMC11026187
- DOI: 10.1007/s10865-023-00446-2
Effects of a medication adherence app among medically underserved adults with chronic illness: a randomized controlled trial
Abstract
For individuals living with a chronic illness who require use of long-term medications, adherence is a vital aspect of successful symptom management and outcomes. This study investigated the effect of a smartphone app on adherence, self-efficacy, knowledge, and medication social support in a medically underserved adult population with various chronic illnesses. Participants were randomized to a group who used the app for one month or a control group provided with a printed medication list. Compared to the control group, participants receiving the intervention had significantly greater medication adherence (Cohen's d = -0.52, p = .014) and medication self-efficacy (Cohen's d = 0.43, p = .035). No significant effects were observed related to knowledge or social support. The findings suggest use of the app could positively impact chronic disease management in a medically underserved population in the United States.
Trial registration: ClinicalTrials.gov NCT05098743.
Keywords: Medically underserved populations; Medication adherence; Medication self-efficacy; Mobile phone applications.
© 2023. The Author(s).
Conflict of interest statement
None declared.
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References
-
- Abel WM, Efird JT, Crane PB, Ferdinand KC, Foy CG, DeHaven MJ. Use of coaching and technology to improve blood pressure control in black women with hypertension: Pilot randomized controlled trial study. The Journal of Clinical Hypertension. 2023;25(1):95–105. doi: 10.1111/jch.14617. - DOI - PMC - PubMed
-
- Anderson-Lewis C, Darville G, Mercado RE, Howell S, Di Maggio S. mHealth technology use and implications in historically underserved and minority populations in the United States: Systematic literature review. JMIR mHealth and uHealth. 2018;6(6):e128–e128. doi: 10.2196/mhealth.8383. - DOI - PMC - PubMed
-
- Anglada-Martinez H, Martin-Conde M, Rovira-Illamola M, Sotoca-Momblona JM, Sequeira E, Aragunde V, Moreno MA, Catalan M, Codina-Jane C. Feasibility and preliminary outcomes of a web and smartphone-based medication self-management platform for chronically ill patients. Journal of Medical Systems. 2016;40(4):99. doi: 10.1007/s10916-016-0456-y. - DOI - PubMed
-
- Avegno KS, Roberson KB, Onsomu EO, Edwards MF, Dean EL, Bertoni AG. Evaluating a telephone and home blood pressure monitoring intervention to improve blood pressure control and self-care behaviors in adults with low-socioeconomic status. International Journal of Environmental Research and Public Health. 2023;20(7):5287. doi: 10.3390/ijerph20075287. - DOI - PMC - PubMed
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